Tianeptine is a selective serotonin reuptake enhancer, possessing strong antidepressant and anxiolytic properties. Its relative lack of sedative, anticholinergic and cardiovascular side effects makes it a highly tolerable substance of abuse. However, physical dependence quickly develops and withdrawal symptoms are common. Abusers in Georgia and Armenia use tianeptine by intravenous injection. D...

We had shown that striatal DA D2 receptors levels predicted the reinforcing responses to the psychostimulant drug methylphenidate in nondrug-abusing subjects. Here, we assessed the replicability of this finding. We measured D2 receptors with PET and [(11)C]raclopride (twice to determine stability) in seven nondrug-abusing subjects to assess if they predicted the self-reports of "drug-liking" to...

What is known about drug treatment effectiveness is based primarily on studies involving men. Little is know about treatment effectiveness for women, particularly pregnant women. Available research and clinical evidence demonstrate that some types of drug treatment can have positive effects in such areas as drug use, employability, and criminal behavior. Drug treatment modalities include reside...

As described by the authors, a recovery-oriented system of care for drug-abusing criminal offenders is one that provides for continuity of treatment, using evidence-based interventions at every stage as clients progress through the justice system. Treatment Alternatives for Safe Communities of Illinois has partnered with criminal justice and treatment programs to establish a basic recovery-orie...

Background: Drug abuse is one of the important variables influencing protective sexual behavior. The objective of this study was to explore how risky sexual behaviors develop in drug abusing women using human ecological theory.Methods: In this study, we used a descriptive exploratory approach. The participants were 32 drug abusing women from two of the selected drop-in centers (DICs) in south T...

BACKGROUND Commonly, cocaine abusing patient are scheduled for elective surgery with a positive urine test for cocaine metabolites. As many of these patients were clinically non-toxic [normal arterial pressure and heart rate, normothermic, and a normal (or unchanged from previous) ECG, including a QTc interval <500 ms], we have recently proceeded with elective surgery requiring general anaesthe...

all people who are active in the field of psychiatry have witnessed upset and disturbed faces of children of substance dependent parents. these children suffer from depression, feelings of shame and low self-esteem and often cope with unhealthy defense mechanisms. most of the times, the addiction problem is kept as a secret and parents mistakenly assume they could keep out their children from t...