Tincture of the dry herb has been used for ages in Uyghur folk medicine to treat heart disease, blood pressure, angina, tracheitis, atherosclerosis, neuralgia, migraine, and headache and toothache. 3 Since the 1970s, 246 compounds, including terpenoids,steroids, flavonoids, alkaloids, lignans, phenols, coumarins, and cyanogenicglucosides, have been identified from the genus Dracocephalum, and t...

Feline calicivirus is one of the surrogate viruses human norovirus. This study aimed to identify virucidal compounds, chemical constituents plants from genus Dracocephalum, which are rich in flavonoids and phenylpropanoid oligomers. Four undescribed including a flavanone glucoside, two stilbenoid glycosides, amide glycoside, as well 17 known were isolated Mongolian Dracocephalum fruticulosum St...

Background: Liver cancer is the second outstanding reason for cancer-related death global and thus a main public health challenge. Plant-based drugs are regarded as promising therapies. Basil and Dracocephalum kotschyi extracts have shown therapeutic impacts on various cancers. Therefore, we assessed the effects of the extract of Basil and Dracocephalum kotschyi on cell proliferation and BCL2 e...

Background and objectives: Dracocephalum kotschyi is a plant which belongs to the Lamiaceae family and exists mostly in south-west Asian countries, including Iran. This plant is used as antispasmodic, analgesic and anti-inflammatory to treat rheumatoid diseases. Methods: In order to investigate the impact of the harvesting time changes on the quantity and quality of monoand sesquiterpenoid comp...

The aim of our study was to investigate the intrinsic diversity of genus based on chemical composition of natural extracts of Cacalia, Dracocephalum, Jatropha, Saussurea and Senecio. Four rarefaction approaches (richness, Shannon’s entropy, Simpson’s diversity, and max-entropy) were implemented as an algorithm and run 10,000 times. Our results showed similar patterns of richness in natural comp...

We established sterile clones of a medicinal plant dragonhead Dracocephalum charkeviczii Prob. (Lamiaceae). used shoots the plants from natural habitat, notably leaf nodes with axillary bud, as explants, sterilized explants in 0.1 % Diocide for 4 minutes and cultivated them on agarized nutrient half-strength MS medium vitamins, 2 sucrose, 0.4 agar, 1 mg/l indolylbutyric acid (IBA), or 0.5 1.0 6...

Background: Breast cancer is the most prevalent malignancy among women in the worldwide and the outbreak in Iranian women is growing. Iranian patients with breast cancer are younger than their Western counterparts. Dracocephalum kotschyi is a wild-growing flowering plant belonging to the family Labiatae and found in Iran. This plant has been applied in Iran folk medicine. The aim of this study ...