Specific problematic issues addressed , page 8 Vygotsky's theory of learning and development, page 9 Subsequent developments in the Cultural-Historical Theory as a foundation for instructional practices, page 13 Description of the innovation, page 17 The authors are responsible for the choice and presentation of the facts contained in this publication and for the opinions expressed therein, whi...

introduction: the major histocompatibility complex (mhc) is a group of cell surface proteins that are essential for recognizing foreign molecules in human and other mammals. the physiologic function of mhc molecules is the presentation of peptides to t cells. in this study, we evaluated the purification of a class ii mhc molecule (hla-dr) from a human burkitt′s lymphoma cell line; daudi. materi...

Dr Deniz Aslan is a Consultant Psychologist and Lecturer, based at Department of Psychology, Roehampton University, London, UK and Langford Clinic, East Sussex, UK. Robert Edelmann is a Professor of Forensic and Clinical Psychology, Dr Diane Bray is the Head of Department and Dr Marcia Worrell is a Principal Lecturer, all are based at Department of Psychology, Roehampton University, London, UK....

Several weeks after the test, Mr Jones learned that he tested positive for a mutation and was sent a form letter stating that “men with this mutation have a 6 percent chance of developing breast cancer and a 7 percent chance of developing prostate cancer before age 70.” Concerned about his results, he went to see Dr Seelinn to find out what he should do with this new information. As he handed D...

Scientific objective: In a recent blog post Dr Andrew Thorburn 1asks why many published discoveries cannot be replicated. He summarizes examples from Dr Glenn Begley (Vice President for oncology at Amgen) that show how Amgen has been unable to reproduce many high-profile discoveries. Dr Thorburn raises the possibility that ‘sloppy science’ may partly explain our inability to measurably improve ...

Power companies such as Southern California Edison (SCE) uses Demand Response (DR) contracts to incentivize consumers to reduce their power consumption during periods when demand forecast exceeds supply. Current mechanisms in use offer contracts to consumers independent of one another, do not take into consideration consumers’ heterogeneity in consumption profile or reliability, and fail to ach...