OBJECTIVE To analyze adverse events following vaccinations against diphtheria, pertussis and tetanus (AEFV-DPT) and to investigate factors associated with event severity. METHODS A cross-sectional study was carried out with a descriptive and analytical component covering AEFV-DPT that were notified in the State of São Paulo, Brazil, between 1984 and 2001, among children less than seven years ...

Diphtheria, Pertussis and Tetanus (DPT) are the vaccine preventable diseases of childhood. The published literatures and reports related to DPT immunization coverage are relatively more than DPT diseases. The striking reduction in deaths and in the incidence of these diseases has been closely associated with the introduction of specific vaccination program. Expanded Program on Immunization (EPI...

1 Dpt. of Engineering Systems and Management, Aeromechanical Systems Group Cranfield University, Shrivenham, Swindon SN6 8LA, United Kingdom. E-mail: [email protected] 2 Dpt. of Engineering Systems and Management, Aeromechanical Systems Group Cranfield University, Shrivenham, Swindon SN6 8LA, United Kingdom. E-mail: [email protected] 3 Dpt. of Informatics and Sensors, Autonomo...

BACKGROUND Dendritic cell (DC)-based vaccines are currently being evaluated as a novel strategy for tumor vaccination and immunotherapy. However, inducing long-term regression in established tumor-implanted mice is difficult. Here, we show that deoxypohophyllotoxin (DPT) induces maturation and activation of bone marrow-derived DCs via Toll-like receptor (TLR) 4 activation of MAPK and NF-κB. M...

The hematopoietic marrow microenvironment is composed of multiple cell types embedded in an extracellular matrix (ECM). We have explored marrow ECM using mass spectrometry and found dermatopontin (DPT), a small non-collagenous ECM protein, to be present. We found that DPT cooperates with other ECM proteins to promote hematopoietic cell adherence in vitro on plastic as well as OP9 stromal cells....

OBJECTIVES Assessment of aortic regurgitation (AR) immediately after transcatheter aortic valve replacement (TAVR) is essential to guide further intervention in cases of relevant AR. It was the aim of this study to identify a simple and reproducible hemodynamic parameter for the assessment of AR. BACKGROUND Relevant AR after TAVR is present in up to 21% of cases and might be associated with a...

Teaching patients about pain: It works, but what should we call it? Adriaan Louw PT, PhD, Emilio “Louie” J. Puentedura PT, DPT, PhD & Kory Zimney PT, DPT To cite this article: Adriaan Louw PT, PhD, Emilio “Louie” J. Puentedura PT, DPT, PhD & Kory Zimney PT, DPT (2016) Teaching patients about pain: It works, but what should we call it?, Physiotherapy Theory and Practice, 32:5, 328-331, DOI: 10.1...

an improved and facile preparation of 3,7-dinitro-1,3,5,7-tetraazabicyclo [3,3,1] nonane(dpt) has been developed starting from urea. in the procedure dpt was synthesized vian,n’-dinitrourea (dnu) as intermediate and various operating parameters such astemperature, ph and molar ratio of reagents have been optimized to give maximum yield ofthe desired product. the low cost method is concise, oper...

Dermatopontin (DPT), a tyrosine-rich, acidic matricellular protein, has been implicated in several human cancers. However, its biological functions and molecular mechanisms in cancer progression, particular hepatocellular carcinoma (HCC), remain unknown. We demonstrated that DPT was significantly down-regulated in 202 HCC clinical samples and that its expression level was closely correlated wit...