AIMS To evaluate the dosimetric profile among three-dimensional conformal radiotherapy (3D-CRT) and stereotactic radiotherapy (SRT) for the treatment of intracranial tumors. MATERIALS AND METHODS Seventeen patients with intra cranial tumors of benign nature or low malignant potential were enrolled and planned for SRT as well as 3D-CRT. Dosimetric comparison between these two plans was done co...

The main goal in this paper is to quantify the quality of different techniques for radiation treatment plans, a back-propagation artificial neural network (ANN) combined with biomedicine theory was used to model thirteen dosimetric parameters and to calculate two dosimetric indices. The correlations between dosimetric indices and quality of life were extracted as the features and used in the AN...

Radon is a natural radioactive gas derived from geological materials. It has been estimated that about half of the total effective dose received by human beings from all sources of ionizing radiation is attributed to 222Rn and its short-lived progeny. In this paper, the use of human respiratory tract models to assess the health hazard from environmental radon is reviewed. A short history of dos...

PURPOSE The aim of this study was to investigate radiation pneumonitis and its associated risk factors in patients with non-small-cell lung cancer treated with concurrent erlotinib and thoracic radiotherapy. MATERIALS AND METHODS We conducted an analysis of patients with nonoperable stage IIIA-IV non-small-cell lung cancer who were treated with concurrent thoracic radiotherapy and erlotinib (...

Modern treatment planning systems provide accurate dosimetry in heterogeneous media (such as a patient' body) with the help of tissue characterization based on computed tomography (CT) number. However, CT number depends on the type of scanner, tube voltage, field of view (FOV), reconstruction algorithm including artifact reduction and processing filters. The impact of these parameters on CT to ...

This study was designed to evaluate dosimetric, pharmacokinetic, and other treatment-related parameters as predictors of outcome in patients with advanced B-lymphocytic malignancies. Fifty-seven patients were treated with radiolabeled Lym-1 antibody in early phase trials between 1985 and 1994. Logistic regression and proportional hazards models were used to evaluate treatment parameters for the...

Background: Recently, multileaf collimators (MLC) have become an important part of any LINAC collimation system because they reduce the treatment planning time and improve the conformity. Important factors that affect MLCs collimation performance are leaves material composition and their thickness.Objective: In this study, we investigate main dosimetric parameters of a typical MLC includi...

BACKGROUND The purpose of this study was to investigate the differences in the dosimetric advantage of using intraoperatively built custom-linked (IBCL) seeds between permanent iodine-125 (I-125) seed implantation (PI) alone and PI followed by external-beam radiation therapy (EBRT) for prostate cancer. METHODS We reviewed the records of 62 patients with localized prostate cancer who received ...