The purpose of this study was to evaluate adaptive daily planning for cervi-cal cancer patients who underwent high-dose-rate intracavitary brachytherapy (HDR-BT) using comprehensive interfractional organ motion measurements. This study included 22 cervical cancer patients who underwent 5 fractions of HDR-BT. Regions of interest (ROIs) including high-risk clinical tumor volume (HR-CTV) and organ...

BACKGROUND To compare volumetric modulated arc therapy (VMAT) with conventional step and shoot intensity modulated radiation therapy (s-IMRT) in nasopharyngeal carcinoma (NPC) patients, and identify which T category patient gains the maximum benefit from VMAT. METHODS Fifty-two patients that randomly selected from 205 patients received VMAT at a single center were retrospectively replanned wi...

The aim of the present study was to compare the dosimetry features of volumetric-modulated arc therapy (VMAT) and fixed field intensity-modulated radiotherapy (f-IMRT) in postoperative irradiation of stage IB-IIA high-risk cervical cancer. Fifteen patients exhibiting stage IB-IIA high-risk cervical cancer, who had been treated with postoperative adjuvant concurrent radiochemotherapy, were selec...

BACKGROUND AND PURPOSES To compare the dosimetry for the left-sided breast cancer treatment using five different radiotherapy techniques. MATERIALS AND METHODS Twenty patients with left sided breast cancer were treated with conservative surgery followed by radiotherapy. They were planned using five different radiotherapy techniques, including: 1) conventional tangential wedge-based fields (TW...

Introduction: Intensity Modulated Radiotherapy (IMRT) is a common method for treating prostate cancers. Different IMRT methods can apply for irradiating the prostate, but there is not clear that which of these methods can provide better dose distribution for each patient individually. Therefore, the aim of this study was to evaluate the relationship between the different prosta...

BACKGROUND In combined proton-carbon fixed-nozzle treatment facilities with raster scanning delivery, the scattering of proton pencil beams caused by nozzle elements and the relatively large nozzle-to-isocenter distance cause a beam broadening. This may pose limitations to the achievable dose conformity. One way to counteract this effect is by delivering the treatment in a position closer to th...

Purpose The purpose of this study was to establish a dosimetric correlation between the bladder volume and its effects on the dose received by the organs at risk (OARs) (urinary bladder, rectum, and sigmoid) during computed tomography (CT)-guided high-dose-rate (HDR) brachytherapy in carcinoma cervix, and to determine an optimum bladder volume to limit the dose to OARs. Material and methods S...

PURPOSE To determine the optimal location of catheters in multichannel vaginal applicators to appropriately cover the vaginal cuff target and minimize dose to the organs at risk (OARs) and hot spots in the target. METHODS A new multichannel vaginal applicator with a diameter of 30 mmconsists of a single central catheter and an outer array of eight catheters. A total of 20 plans were generated...

In this study, we evaluate dosimetric advantages of using patient-specific aperture system with intensity-modulated proton therapy (IMPT) for head and neck tumors at the shallow depth. We used four types of patient-specific aperture system (PSAS) to irradiate shallow regions less than 4 g/cm2 with a sharp lateral penumbra. Ten head and neck IMPT plans with or without aperture were optimized sep...

Background and purpose Delineation of organs at risk (OARs), such as the bladder, rectum sigmoid, plays an important role in delivery optimal absorbed dose to target owing steep gradient high-dose rate brachytherapy (HDR-BT). In this work, we propose a deep convolutional neural network-based approach for fast reproducible auto-contouring OARs HDR-BT. Materials methods Images 113 patients with l...