Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

background: in neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors loaded with these materials.   objective: the purpose of this study is to evaluate dose distribution in the presence of  10 b ,  157 gd  and  33 s  ne...

objective: due to recent advances in nanotechnology it is now possible to accumulate high atomic-number nanomaterial such as gold nanoparticles (gnps) in cancerous cells and take advantage of their absorbed dose enhancement property as radiosensitizing agents. this study aimed to investigate the absorbed dose enhancement factor due to the presence of pegylated gnps under the irradiation of an m...

Background: In neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors loaded with these materials. Objective: The purpose of this study is to evaluate dose distribution in the presence of 10B, 157Gd and 33S neutron...

Introduction In this study, we aimed to calculate dose enhancement factor (DEF) for gold (Au) and iron (Fe) nanoparticles (NPs) in brachytherapy and teletherapy, using Monte Carlo (MC) method. Materials and Methods In this study, a new algorithm was introduced to calculate dose enhancement by AuNPs and FeNPs for Iridium-192 (Ir-192) brachytherapy and Cobalt-60 (Co-60) teletherapy sources, using...

Background: The amount of average dose enhancement in tumor loaded with 10B may vary due to various factors in boron neutron capture therapy.Objective: This study aims to evaluate dose enhancement in tumor loaded with 10B under influence of various factors and investigate the dependence of this dose enhancement on neutron spectra changes.Material and Methods: In this simulation stud...

background: new treatment modalities are developed with the aim of escalating tumor absorbed dose and simultaneously sparing the normal structures. the use of nanotechnology in cancer treatment offers some possibilities including destroying cancer tumors with minimal damage to healthy tissues. zinc oxide nanoparticles (zno nps) are wide band gap semiconductors and seem to have a good effect on ...

Background: External beam radiation therapy is often administered to patients implanted with silicone gel breast prosthesis. The aim of this study was to investigate the influence of silicone gel breast prosthesis on photon dose distributions. In the event of recurrence, the oncologist may be forced to irradiate through the prosthetic device. To quantify the dose enhancement or reduction below ...

introduction magnetic fields are capable of altering the trajectory of electron beams andcan be used in radiation therapy.theaim of this study was to produce regions with dose enhancement and reduction in the medium. materials and methods the ndfeb permanent magnets were arranged on the electron applicator in several configurations. then, after the passage of the electron beams (9 and 15 mev va...

conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...