the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

since hospitals are an important and integral part of the overall health delivery system, this study was carried out to measure the effectiveness of this institution within the system. the records of 633 hospitalized patients in the pediatrics ward of ghaem hospital in mashhad during 1357 (21 march 1978-20 march 1979) has been consulted. more than half of the patients were hospitalized with the...

intravitreal injection is the most common approach for drug delivery to the posterior segment in humans. however, following the injection, drugs are rapidly eliminated from the vitreous, with half-lives up to a few days. depending on the rate of clearance from the vitreous, large boluses and frequent administrations may be required to ensure therapeutic levels over an extended period of time. m...

objective (s): transdermal preparations for testosterone are becoming popular because of their unique advantages such as avoidance of first-pass effect, convenience, improved bioavailability, and reduction of systemic side effects. a novel testosterone transdermal delivery system (tdds) was developed using a palm oil base called hamintm (a commercial product) and tested using in vitro and in vi...

introduction today, there is a growing interest in the use of hadrontherapy as an advanced radiotherapy technique. hadrontherapy is considered a promising tool for cancer treatment, given its high radiobiological effectiveness and high accuracy of dose deposition due to the physical properties of hadrons. however, new radiation modalities of dose delivery and on-line beam monitoring play crucia...

introduction intensity modulated radiation therapy (imrt) has made a significant progress in radiation therapy centers in recent years. in this method, each radiation beam is divided into many subfields that create a field with a modulated intensity. considering the complexity of this method, the quality control for imrt is a topic of interest for researchers. this article is about the various ...