نتایج جستجو برای: dopamine antagonist

تعداد نتایج: 100668  

F Rastegar H Zartab HR Samiee P Alagheband R Zarrindast S Fazli Tabaei S Safari SH Yahyavi

In the present study, interactions of dopamine receptor agonists and antagonists with water swimming stress (WSS) on naloxone-induced jumping in morphine-dependent mice were examined. Mice were rendered dependent as described in the methods section. The opioid receptor antagonist, naloxone (1 mg/kg), was injected to elicit jumping (as a withdrawal sign). The first group exposed to WSS in the pr...

کریمیان, سیدمرتضی, دهپور, احمدرضا , پرویز, محسن , کشاورز, منصور ,

In this study the effects of bromocriptine and apomorphine (dopamine receptor agonists) on electrical field induced twitch response of longitudinal muscle of guinea-pig illeum was investigated. Bromocriptine and apomorphine dose dependently inhibited illeal contraction. IC50 for this inhibitory effects were 6.22±0.645×10^-7 M and 5.48±0.647×10^-6 M, respectively. sulpiride (a specific D2 dopami...

F Rastegar H Zartab HR Samiee P Alagheband R Zarrindast S Fazli Tabaei S Safari SH Yahyavi

In the present study, interactions of dopamine receptor agonists and antagonists with water swimming stress (WSS) on naloxone-induced jumping in morphine-dependent mice were examined. Mice were rendered dependent as described in the methods section. The opioid receptor antagonist, naloxone (1 mg/kg), was injected to elicit jumping (as a withdrawal sign). The first group exposed to WSS in the pr...

احتشامی , سارا, خانی , حسن, فرزین , داوود,

Background and purpose : Âscorbic acid, an antioxidant vitamine, is found throughout the mammalian central nervous system (ÇNS). There is evidence that it may modulate neuronal activity, release of neurotransmitters and dopamine receptors activities. There are behavioral evidences supporting the antidopaminergic effect of ascorbic acid. This effect of ascorbic acid may, in part, modulate the ...

B HASHEMI, MR ZARRINDAST, V TOLUI,

In this study, the influence of dopamine receptor agonists and antagonists on antinociception induced by bac10fen has been examined in the formalin test. The GABA-B agonist bac10fen induced antinociception in both phases of the formalin test in mice. The dopamine receptor agonists SKF 38393 and quinpirole also induced antinociception in both phases of the test. SKF 38393 but not quinpirole ...

Journal: :medical journal of islamic republic of iran 0
mr zarrindast from the department of pharmacology, school of medicine, tehran university of medical sciences, tehran, i.r. iran. b hashemi v tolui

in this study, the influence of dopamine receptor agonists and antagonists on antinociception induced by bac10fen has been examined in the formalin test. the gaba-b agonist bac10fen induced antinociception in both phases of the formalin test in mice. the dopamine receptor agonists skf 38393 and quinpirole also induced antinociception in both phases of the test. skf 38393 but not quinpirole pote...

MOHAMMAD HOSSEIN POURGHOLAMI, MOHAMMAD-REZA ZARRINDAST, YADOLLAH KHAlENABI,

Intraperitoneal (IP) injection of bupropion (3,6, amine (4,16 mg kg•') induced dose-dependent climbing in mice. The climbing response induced by both drugs were decreased in animals pretreated either with the 0-1 antagonist SCH 233<)0 or the 0-2 antagonist sulpiride. The α-adrenoceptor blocker phenoxybenzamine decreased the climbing induced by both bupropion and amphetamine, but the β-ad...

Journal: :medical journal of islamic republic of iran 0
mohammad-reza zarrindast from the department of pharmacology, faculty of medicine, tehran university of medical sciences, tehran, islamic republic of iran. yadollah khalenabi mohammad hossein pourgholami

intraperitoneal (ip) injection of bupropion (3,6, amine (4,16 mg kg•&apos;) induced dose-dependent climbing in mice. the climbing response induced by both drugs were decreased in animals pretreated either with the 0-1 antagonist sch 233<)0 or the 0-2 antagonist sulpiride. the α-adrenoceptor blocker phenoxybenzamine decreased the climbing induced by both bupropion and amphetamine, but the β-adre...

Introduction: The hippocampus (HIP), the primary brain structure related to learning and memory, receives sparse but comprehensive dopamine innervations and contains dopamine D1/D2-like receptors. It is demonstrated that dopamine receptors in dentate gyrus (DG) region of HIP have a remarkable function in spatial reward processing. Much less is known about the involvement of HIP and its D1...

Journal: :basic and clinical neuroscience 0
behrooz khakpour-taleghani cellular &amp; molecular research center and department of physiology, school of ‎medicine, guilan university of medical sciences, rasht, iran ‎ zahra reisi neuroscience research center, shahid beheshti university of medical sciences, ‎p.o.box 19615-1178, tehran, iran abbas haghparast neuroscience research center, shahid beheshti university of medical sciences, ‎p.o.box 19615-1178, tehran, iran

introduction: the hippocampus (hip), the primary brain structure related to learning and memory, receives sparse but comprehensive dopamine innervations and contains dopamine d1/d2-like receptors. it is demonstrated that dopamine receptors in dentate gyrus (dg) region of hip have a remarkable function in spatial reward processing. much less is known about the involvement of hip and its d1/d2 do...

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