Surface waters in the Florida Everglades contain high levels of dissolved organic carbon (DOC) compounds. C values of DOC samples collected from the northern Everglades indicate that less than about 23% of the DOC was derived from sugarcane (the dominant agricultural crop in the area), and the amount of DOC from sugarcane was greater during the dry period. Most of the DOC (> 50%) in the norther...

Heated (20 min at 70 degrees C) amphotericin B-desoxycholate (hAMB-DOC) was further characterized, as was another formulation obtained after centrifugation (60 min, 3000 x g), hcAMB-DOC. Conventional AMB-DOC consisted of individual micelles (approximately 4 nm in diameter) and threadlike aggregated micelles, as revealed by cryo-transmission electron microscopy. For both hAMB-DOC and hcAMB-DOC, ...

We investigated the effect of dissolved organic carbon (DOC) on hypolimnetic metabolism (accumulation of dissolved inorganic carbon (DIC) and methane (CH4)) in 21 lakes across a gradient of DOC concentrations (308 to 1540 !mol C L). The highly colored nature of the DOC in these lakes suggests it is mostly of terrestrial origin. Hypolimnetic methane accumulation was positively correlated with ep...

The aim of this work was to evaluate how an aqueous micellar system containing Amphotericin B (AmB) and sodium deoxycholate (DOC) can be rebuilt after heating treatment. Also, a review of the literature on the physicochemical and biological properties of this new system was conducted. Heated (AmB-DOC-H) and unheated (AmB-DOC) micelles were then diluted at four different concentrations (50 mg · ...

It is known that 19-nor-deoxycorticosterone (19-nor-DOC) is a potent mineralocorticosteroid that is present in urine of rats and humans in a free, i.e., nonconjugated, form. In some forms of hypertension in rats, the levels of free 19-nor-DOC in urine are increased compared with those in urine of normotensive animals. Yet, despite the potential importance of this mineralocorticosteroid in the p...

a large portion of municipal waste, disposed in landfills, is organic in nature. this organicmaterial starts decomposing soon after the disposal in landfills. the decomposition leads to the generation ofin situ leachate, and this leachate can contain substantial amounts of contaminants. under arid conditions,leachate is solely generated by waste decomposition, as little input of external water ...

The composition and cycling of high-molecular-weight dissolved organic carbon (HMW-DOC) were examined in a tidal stream (Bayou Trepagnier) with seasonally high DOC concentrations (1.0–5.6 mM). 13C nuclear magnetic resonance (13C NMR) was used to examine the bulk chemical composition of natural HMW-DOC from two field sites over 1.5 yr. The HMW-DOC at both sites was dominated by aliphatic (41%), ...

To investigate the role of the renin-angiotensin system in the regulation of adrenal growth in deoxycorticosterone (DOC)-salt hypertensive rats, and the adrenal gene expression of angiotensin AT1 and AT2 receptors, three groups of uninephrectomized rats + DOC pellet + 0.9% NaCl were given water (DOC), losartan (DOC-L), or ramipril (DOC-R) by gavage. Controls had sham surgery and water gavage. T...

As successful chemotherapy with the taxanes needs to reduce the toxic side effects against normal tissues and avoid the detrimental effects caused by intolerable solvents, drug delivery system using soluble polymeric micelles tends to be the focus. Docetaxel (Doc) has demonstrated extraordinary activities against a variety of solid tumors. However, the clinical efficacy is contrasted by its tox...

Downing, B.D., B.A. Bergamaschi, D.G. Evans and E. Boss. 2008. Estimating source-specific contributions of DOC into a drinking-water reservoir using optical profiling. Lake Reserv. Manage. 24:381–391. Understanding the sources of dissolved organic carbon (DOC) in drinking-water reservoirs is an important management issue because DOC may form disinfection by-products, interfere with disinfection...