نتایج جستجو برای: dna fragmentation index

تعداد نتایج: 922260  

Asuman Demiroglu Zergeroğlu Elif Yılmaz Kenan Sofuoglu Nuri Delikara Pelin Kutlu Seda Yılmaz,

Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...

Journal: :Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2013
Jiri Novotny Nabil Aziz Roman Rybar Jana Brezinova Vera Kopecka Radka Filipcikova Marie Reruchova Ivana Oborna

AIM The aim of this prospective study was to find possible relationship between ROS production measured by chemiluminescence and flow cytometry in human semen and sperm DNA damage estimated by Sperm Chromatin Structure Assay. METHODS Study included 39 men from infertile couples and 23 fertile volunteers who served as a control group. Aliquot of neat semen was used for ROS detection by chemilu...

Journal: :international journal of reproductive biomedicine 0
zohreh khodayari naeini hassan hassani bafrani hossein nikzad

background: an effect of cryopreservation on human sperm is sublethal cryodamage, in which cell viability post-thaw is lost more rapidly at later times than in fresh cells. objective:  this study examined whether the addition of an antioxidant to cryopreservation medium could improve the post-thaw parameters and evaluation of sperm chromatin quality of cryopreserved human spermatozoa from men w...

2017
Carlos Duarte Víctor Núñez Yat Wong Carlos Vivar Elder Benites Urso Rodriguez Carlos Vergara Jorge Ponce

BACKGROUND In assisted reproduction procedures, we need to develop and enhance new protocols to optimize sperm selection. The aim of this study is to evaluate the ability of the Z potential technique to select sperm with intact DNA in non-normospermic patients and evaluate the impact of this selection on embryonic development. METHODS We analyzed a total of 174 human seminal samples with at l...

Adel Zalata Ayman Z El-Samanoudy Dalia Shaalan Taymour Mostafa, Youssef El-Baiomy

Background Use of cellular phones emitting radiofrequency electromagnetic field (RF-EMF) has been increased exponentially and become a part of everyday life. This study aimed to investigate the effects of in vitro RF-EMF exposure emitted from cellular phones on sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU) gene expression. MaterialsAndMethods In this prospective stud...

Gholamian M, Jalali M Shamsa A

Background: Techniques of sperm preparation require centrifugation to separate spermatozoa from the seminal plasma. The centrifugation can induce damage to the spermatozoa and increase reactive oxygen species(ROS) productionspecially in leukospermic speciemens that are associated with impaired function and fertilizing capacity. However in ICSI, fertilization can occure with damage DNA sperm but...

Journal: :international journal of fertility and sterility 0
seda yılmaz asuman demiroglu zergeroğlu elif yılmaz kenan sofuoglu nuri delikara pelin kutlu

background: sperm dna fragmentation is known as an important cause of male infertility. the influence of sperm dna damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. in this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (icsi) outcome according to sperm dna fragme...

Hoseinifar H Modaressi T Sabbaghian M Sadighi Gilani MA Yazdanikhah S

Background: Infertility is estimated to affect up to 15% of couples of reproductive age, and male factors contribute to 50% of these cases. Globozoospermia syndrome is a severe form of teratozoospermia, with an incidence of less than 0.1%. It is characterized by round sperm head. The most prominent feature of globozoospermia is the malformation of the acrosome, which is totally absent in the to...

Journal: :international journal of environmental research 0

the objectives of this work was to examine the toxicological effect and molecular changes caused by a heavy metal pollutant mercuric chloride (hgcl2), in fresh water snakehead channa punctatus, locally known as taki fish in bangladesh. when fishes were exposed to hgcl2, it induced death of the fishes in a concentration-dependent manner. 1 mm, the highest concentration tested in this study, was ...

Journal: :jundishapur journal of natural pharmaceutical products 0
marzieh jafari department of pharmacology and toxicology, school of pharmacy, ahvaz jundishpur university of medical sciences, ahvaz, ir iran mohsen rezaei department of pharmacology and toxicology, school of pharmacy, ahvaz jundishpur university of medical sciences, ahvaz, ir iran; department of pharmacology and toxicology school of pharmacy, ahvaz jundishpur university of medical sciences, ahvaz, ir iran. tel: +98-9167250548, fax: +98-6113738381 heibatullah kalantari department of pharmacology and toxicology, school of pharmacy, ahvaz jundishpur university of medical sciences, ahvaz, ir iran mahmoud hashemitabar cellular and molecular research center, ahvaz jundishpur university of medical sciences, ahvaz, ir iran

background apoptosis or programmed cell death is an essential process for elimination of damaged cells. also, induction of apoptosis is fundamental for treating cancer. screening for agents that induce apoptosis in tumor cells help in the development of novel agents for cancer treatment. numerous studies suggest that the exposure of tumor cells to statins can lead to cell death via two separate...

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