Membrane-associated guanylate kinases (MAGUKs) are a large family of scaffold proteins that play essential roles in tissue developments, cell-cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. Here we show that the GK domai...

This paper adopts the stochastic simulation method that pertains to geostatistics, on the basis of simulated DEM realizations with spatial autocorrelation errors, to explore the error propagation mechanism of DEM-DON-DLG under the digital photogrammetry environment. It follows this procedure: first, produce 100 error-disturbed DEMs by means of sequential Gaussian simulation; next, attain 100 re...

The nonlocal nonlinear buckling of a double layer graphene sheet (DLGS) covered by zinc oxide (ZnO) piezoelectric layers is investigated in this study. The surrounding circumstances of the system are considered as a Pasternak foundation including spring constants and a shear layer. Graphene sheets are subjected to longitudinal magnetic field and biaxial forces. On the other hand, the ZnO piezoe...

1 Karel Kreijns, Open University of the Netherlands, Faculty of Technical Sciences, Heerlen, The Netherlands, [email protected] 2 Paul A. Kirschner, Open University of the Netherlands, Educational Technology Expertise Center, Heerlen, The Netherlands, [email protected] Abstract  Our research on enhancing and fostering social interaction in asynchronous distributed learning groups (DLGs) u...

A new architecture for the World Wide Web is emerging, known as the Semantic Web. In broad terms, it encompasses efforts to populate the Web with content which has formal semantics. This will enable automated agents to reason about Web content, and produce an intelligent response to unforeseen situations. We believe that in order to build the Semantic Web, the sharing of ontological information...

We present our theoretical comparisons and experimental evaluations of three boundary data representations in terms of storage and information retrieval efficiency. We focus on three boundary data representations, such as, location list data structure (LLS), digital line graphs (DLGs) and topologically integrated geographic encoding and referencing (TIGER) data organizations. These three bounda...

| Membrane-associated guanylate kinases (MAGUKs) are a family of scaffold proteins that are highly enriched in synapses and are responsible for organizing the numerous protein complexes required for synaptic development and plasticity. Mutations in genes encoding MAGUKs and their interacting proteins can cause a broad spectrum of human psychiatric disorders. Here, we review MAGUK-mediated synap...

The topography of a catchment has a major impact on the hydrological, geomorphological. and biological processes active in the landscape. The spatial distribution of topographic attributes can often be used as an indirect measure of the spatial variability of these processes and allows them to be mapped using relatively simple techniques. Many geographic information systems are being developed ...

Use of citations and web links embedded in online teaching materials was studied for an undergraduate course. The undergraduate students enrolled in Geographic Information Science for Geography and Regional Development used web links more often than citations, but clearly did not see them as key to enhancing learning. Current conventions for citing and linking tend to make citations and links i...