Medicine, like scientific inquiry, is necessarily dynamic. As our understanding of health and disease continues to grow, medicine as we know it will change. Alternative therapies and perspectives that are coming to light will be illuminated by modern methods of inquiry applied to pre-modern healing systems. At the same time, patient demands and cultural concerns about health and healing influen...

The total genomic mutation rate (μ) and the deleterious mutation rate ( U ), are of fundamental importance to a number of areas of biology, including the classic evolutionary conundrum: why sex? Unfortunately, both μ and U have historically proven extremely difficult to measure accurately. A recent study by Haag-Liautard et al. (1) combines traditional experimental ’mutation accumulation’ metho...

In a place at La Mancha El Quijote decided to go out as a knight-errant in search of adventure. In one of his escapades El Quijote met Master Pedro and his divining past-things ape. Master Pedro was a famous puppet-showman, exhibiting a show of the release of Melisendra and thus, for the very first time in our history, he linked marketing and technology. The Master Pedro’s show was mainly used ...