1 These ingredients are nonmonograph except when used to prepare acidulated phosphate fluoride treatment rinses identified in § 355.10(a)(3) of this chapter. for marketing. In the absence of an approved new drug application or abbreviated new drug application, such product is also misbranded under section 502 of the act. (c) Clinical investigations designed to obtain evidence that any drug prod...

A selective and sensitive liquid chromatographic method has been developed for simultaneous determination of zonisamide and its four related substances in pharmaceutical dosage forms. The assay involved an isocratic elution in perfectsil Target C18 column using a mobile phase composition of disodium hydrogen phosphate buffer, acetonitrile and methanol (650:150:200 v/v, pH adjusted to 3±0.05) wi...

• Non-toxic acellular design of a dual crosslinked hyaluronic acid (HA) hydrogel Hydrogen phosphate ions form physical crosslinks with cystamine-crosslinked HA Salt treatment is non-toxic and generates cell-migrating aggregated structures Physical act as nucleation site for hydroxyapatite mineralisation Hydroxyapatite crystals were accomplished across the in simulated body fluid The creation (H...

The hydrolysis of potato starch by pancreatin has been the subject of much investigation, particularly by Sherman and his pupils (I), who have studied the action of both malt and pancreatic amylase upon potato starch, especially with reference to optimum concentration of enzyme, substrate, pH value, and concentration of activating salts. The best conditions of hydrolysis were at (2) 40” in the ...

introduction: one of the hypotheses regarding the calcification induction by mineral trioxide aggregate (mta) is the involvement of transforming growth factor-beta (tgf- β ) super family. calcium-enriched mixture (cem) cement is one of the endodontic biomaterials with clinical applications similar to mta. the aim of the present in vitro study was to compare the induction of bone morphogenic pro...

An enzymatic method for ready access to D-sedoheptulose-7-phosphate on a preparative scale was developed, based on the irreversible transketolase-catalyzed reaction: β-hydroxypyruvate + D-ribose-5phosphate → D-sedoheptulose-7-phosphate. D-Sedoheptulose-7-phosphate disodium salt was obtained in 81% overall yield determined using a standard curve obtained by LC/MS/MS.