Aim: The emergence of nosocomial infections, which are mainly transmitted by contaminated instruments, there is an urgent need of a novel disinfecting agent, which can able to act by the novel method with less residual concentration. Evaluation of antibacterial activity of thymol-eugenol mixture for potential application as disinfectant agent. Methods: The reference strains of Escherichia coli,...

44 BioPharm International FEBRUARY 2003 regulatory authorities, and it is also critical to ensuring worker safety when dealing with high-risk materials. A disinfectant has been defined as “an agent that frees from infection; usually a chemical agent that destroys disease germs or other harmful microorganisms or inactivates virus” (6). In this article, disinfectants targeted to specific viruses ...

Newborns are more susceptible to infection; this makes proper wound care extremely important in them. Unfortunately, in spite of successful surgery, patients can die as a result of wound area infections. Herein, we report a case in which a combined therapy of chlorhexidine (a disinfectant) and saline (a cleansing agent used in wound care) was used effectively to treat the wound in a newborn inf...

A standardized disinfectant test for Staphylococcus aureus cells in biofilms was developed. Two disinfectants, the membrane-active compound benzalkonium chloride (BAC) and the oxidizing agent sodium hypochlorite, were used to evaluate the biofilm test. S. aureus formed biofilms on glass, stainless steel, and polystyrene in a simple system with constant nutrient flow that mimicked as closely as ...

Chlorine dioxide (ClO2) is an antimicrobial agent recognized for its disinfectant properties. In this study, the sanitizing effects of ClO2 solutions against Salmonella enterica and Erwinia carotovora in water, on tomato surfaces, and between loads of tomatoes were evaluated. In water, ClO2 at 5, 10, and 20 ppm caused a > or = 5-log reduction of S. enterica within 6, 4, and 2 s, respectively. H...

The Minimum Inhibitory Concentration (MIC) Test is an important evaluating tool in the field of microbiology. It gives us an idea of the microbial activity assessment in any source sample containing microbes. Validating the effectiveness of disinfection and decontamination is a vital and often challenging task. In clinical and laboratory environments, presence of sterile conditions is a compuls...

Effective and economical mycobactericidal disinfectants are needed to kill both Mycobacterium tuberculosis and non-M. tuberculosis mycobacteria. We found that acetic acid (vinegar) efficiently kills M. tuberculosis after 30 min of exposure to a 6% acetic acid solution. The activity is not due to pH alone, and propionic acid also appears to be bactericidal. M. bolletii and M. massiliense nontube...