background: small cell lung cancer (sclc) is a highly aggressive tumor.   objective: to evaluate the survival and time to progression of patients with sclc admitted to a chest disease center in istanbul, turkey.   methods: based on the reports of a pulmonary oncology clinic, data regarding performance status (ps), clinical stage of disease, treatment, time to progression and survival of 67 pati...

Background: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression. Methods: In this cross-sectional study, two groups were enroll...

background: studies have shown that zinc and selenium deficiency is common in nonalcoholic fatty liver disease (nafld). however, the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld are not clear enough. the aim of this study was to compare the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld prognos...

multiple sclerosis (ms) is a chronic inflammatory disease that leads to degeneration of the brain and spinal tissue. imbalances of cd4+ t cells including thelper1 (th1)/thelper2 (th2) and thelper17 (th17)/tregulatory (treg), their secreted cytokines and gene expressions, are important aspects of in immunopathogenesis of ms. vitamin a and its metabolites can regulate the immune system and appear...

Background and aim: Vitiligo is an acquired idiopathic hypomelanotic disease. The purpose of this study was to review clinical characteristics of vitiligo and their significance in the progression of vitiligo.Materials and methods: Eight hundreds and sixteen cases of vitiligo were studied from February 2005 to October 2006. All of the patients were referred to dermatolo...

Background: The Multi state Markov models have extensively application with categorization of laboratory marker of CD4 cells for evaluation of HIV disease progression. These models with different states result in different effects of covariates and prediction of HIV disease trend. The main purpose of this study was comparison of four and five states models with the three- state in order to sele...

conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...