نتایج جستجو برای: direct hemolytic

تعداد نتایج: 441922  

Journal: :The Journal of pharmacology and experimental therapeutics 1998
D C McMillan C B Jensen D J Jollow

Dapsone hydroxylamine (DDS-NOH) is a direct-acting hemolytic agent responsible for dapsone-induced hemolytic anemia in the rat. The hemolytic activity of DDS-NOH is associated with the formation of disulfide-linked hemoglobin adducts on membrane skeletal proteins. We have postulated that this membrane protein "damage" is a consequence of DDS-NOH-induced oxidative stress within the red cell and ...

Journal: :Polimeros-ciencia E Tecnologia 2022

To analyze the biocompatibility of scaffold produced from a natural polymer derived castor oil through hemolytic activity and antimicrobial activity, to enable clinical application. Three in vitro tests were performed: Hemolytic test - Polymer partially dissolved contact with blood agar; sheep's extract red cells solution; Antimicrobial Solid direct E. Coli S. Aureus. For tests, none samples sh...

Journal: :The Journal of the Association of Physicians of India 2013
Kaustubh D Salagre Ravindra Nath Sahay Anuja Patil Amita Joshi Akash Shukla

A 48 year old lady presented with jaundice and exertional breathlesness. Her laboratory reports showed anaemia, reticulocytosis, leucocytosis, elevated Lactate Dehydrogenase (LDH), alkaline phosphatase levels, hyperbillirubinemia and positive direct Coomb's test. After ruling out all the other causes of autoimmunity and hemolytic anemia, she was diagnosed as leukemoid reaction due to autoimmune...

Journal: :Haematologica 2013
Mehdi Nouraie Janet S Lee Yingze Zhang Tamir Kanias Xuejun Zhao Zeyu Xiong Timothy B Oriss Qilu Zeng Gregory J Kato J Simon R Gibbs Mariana E Hildesheim Vandana Sachdev Robyn J Barst Roberto F Machado Kathryn L Hassell Jane A Little Dean E Schraufnagel Lakshmanan Krishnamurti Enrico Novelli Reda E Girgis Claudia R Morris Erika Berman Rosenzweig David B Badesch Sophie Lanzkron Oswaldo L Castro Jonathan C Goldsmith Victor R Gordeuk Mark T Gladwin

The intensity of hemolytic anemia has been proposed as an independent risk factor for the development of certain clinical complications of sickle cell disease, such as pulmonary hypertension, hypoxemia and cutaneous leg ulceration. A composite variable derived from several individual markers of hemolysis could facilitate studies of the underlying mechanisms of hemolysis. In this study, we asses...

Journal: :Hematology/oncology clinics of North America 1976
L C Jefferies

Autoimmune hemolytic anemias include warm and cold reactive autoimmune hemolytic anemias (WAIHA and CAD), paroxysmal cold hemoglobinuria (PCH), and drug-induced hemolytic anemias. If autoimmune hemolytic anemia is suspected, the clinical history should be communicated to the transfusion service, because specific tests to confirm these diagnoses are not routinely performed. This includes evaluat...

2012
MALATHI SHEKAR IDDYA KARUNASAGAR INDRANI KARUNASAGAR

V.parahaemolyticus pathogenicity has been associated with its ability to produce thermostable direct hemolysin (TDH) encoded by the tdh gene. Although all V.parahaemolyticus strains possess this gene some strains are hemolytic, intermediate or non-hemolytic. To assess the differences seen, we screened the surface of the TDH proteins showing variable hemolytic activity for identification of poss...

Journal: :The Turkish journal of pediatrics 2016
Aysel Vehapoğlu Nilüfer Göknar Rümeysa Tuna Fatma Betül Çakır

Drug-induced hemolytic anemia is an immune-mediated phenomenon that leads to the destruction of red blood cells. Here, we present a case of life-threatening ceftriaxone-induced hemolytic anemia (CIHA) in a previously healthy 3-year-old girl. We also reviewed the literature to summarize the clinical features and treatment of hemolytic anemia. Acute hemolysis is a rare side effect of ceftriaxone ...

2005
HAL CRAWFORD

By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

2005
MARIE CUTBUSH

By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

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