securigera securidaca (l.) degen & dorfl grows in different parts of iran. the seeds of the species are used in iranian folk medicine as an anti-diabetic agent. many studies have established hypoglycemic effects of amino acids and in the present investigation, amino acids of securigera securidaca seeds have been evaluated. the ground seeds were extracted using petroleum ether, hot ethanol a...

the present work describes the studies on the coordination behaviour of 4[n-(benzalidene) amino]antipyrine semicarbazone (baaps) (i), 4[n-(furfural)amino]antipyrine semicarbazone (ffaaps) (ii) and 4[n-(cinnamalidene)amino]antipyrine semicarbazone (caaps) (iii) in presence of dimethyl sulfoxide (dmso) or diphenyl sulfoxide (dpso) towards th4+ and uo22+ salts. all the complexes were isolated in n...

Metabolites of β2-agonists 2-(4-amino-3,5-dichlorophenyl)-2-(alkylamino)ethanols, derivatives hippuric and mandelic acids, were synthesized. The excretion profiles the target compounds metabolites with urine studied in experiments on laboratory animals. 2-(4-Amino-3,5-dichlorophenyl)-2-(isopropylamino) ethanol (9.7% administered dose) 2-(4-amino-3,5-dichlorophenyl)-2-(tert-amylamino)ethanol (0....

Drynariae rhizoma has been used to prevent bone loss that occurs with increasing age. However, the chemical compounds in extracts that act on bone metabolism in herbal medicine are poorly understood. This study aimed to investigate and compare the extraction efficacy of polyphenolic compounds, antioxidant activity, and in vitro anti-osteoporosis properties of water extract (DR-DW) and ethanol e...

To reduce the leachability of reducing agents from composite resins, immobilization of a simulated reducing agent at the surface of SiO2 fillers was examined. SiO2 plates were immersed in 2% 3-aminopropyltriethoxy silane/ethanol solution, and then immersed in dimethyl sulfoxide with 0.25 wt% 4-dimethyl amino benzoic acid (DMABA), 2.0 wt% 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochlor...

An environment friendly synthesis of 2-amino-3-cyano-4-aryl-7,7-dimethyl-5-oxo-4H-5,6,7,8-tetrahydrobenzo[b]pyran, 2aryl benzimidazole and 2-aryl-4, 5-dihydro-1H-imidazole derivatives using Mg-Al hydrotalcite as an efficient catalyst has been developed. The excellent efficiency of the catalyst can be attributed to its Lewis acidic sites which resulted in higher reaction yields for different sub...

An environmentally friendly, one-pot, three-component synthesis of 8,10-dimethyl-12-aryl-12H-naphtho[1′,2′:5,6]pyrano[2,3-d]pyrimidine-9,11-diones was achieved via coupling aromatic of aldehydes, β-naphthol and 6-amino-1,3-dimethyl uracil in the presence of formic acid as a catalyst under solvent-free conditions at 90 °C. This method has several advantages, such as efficiency, good yield, short...

The title Schiff base compound, C(17)H(19)N(3)O(2), was obtained from the condensation of 4-dimethyl-amino-benzaldehyde with 4-methoxy-benzohydrazide in an ethanol solution. The mol-ecule is twisted with respect to the N-N single bond [C-N-N-C = -159.27 (14)°] and the dihedral angle between the two aromatic rings is 67.1 (2)°. In the crystal structure, the mol-ecules are linked into chains alon...

Solubility of lornoxicam in various pure solvents and solvent-cosolvent mixtures was studied to understand drug vehicle interactions and in order to get the required solubility equal to the dose of lornoxicam, i.e., 4 mg/ml for development of solution formulation. Polyethylene glycol (PEG) 400, propylene glycol, ethanol, water, dimethyl formamide, dimethyl sulfoxide, and ethyl acetate were used...

This study compares the involvement of ATP-sensitive potassium (K(ATP)) channels and prostaglandins in various forms of gastroprotection in the rat. Instillation of 1 ml of 70% ethanol induced severe gastric mucosal damage (lesion index 39 +/- 0.8), which was substantially but not maximally reduced by oral pretreatment with 16,16-dimethyl-prostaglandin (PG) E(2) (75 ng/kg), 20% ethanol (1 ml), ...