Artificial metalloenzymes result from anchoring an organometallic catalyst within evolvable protein scaffold. Thanks to its dimer of dimers quaternary structure, streptavidin allows the precise positioning two metal cofactors activate a single substrate, thus expanding reaction scope accessible artificial metalloenzymes. To validate this concept, we report herein on our efforts engineer and evo...

In this work, an efficient and facile method has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones from a condensation reaction of 2-aminobenzamide with various alkyl,aryl and alicyclic aldehydes or ketones using Fe3O<span class="fontstyle0" styl...