A 7-year-old Korean girl presented with an 8-month history of an erythematous hard plaque on her left hand. There was no history of trauma. On physical examination, a 1.4 0.8-cm firm plaque was observed on the ulnar surface of the left hand at the metacarpophalangeal level (Figure). Histopathologic examination showed moderately cellular fibroblasts throughout the dermis. Hematoxylineosin staini...

  Gardner's syndrome is an autosomal dominant inherited disorder. Familial polyposis of the colon, osteomas, hypertrophy of the retinal-pigmented layer and a multitude of soft tissue tumors are characteristic features. The syndrome may be presented with colonic or extracolonic symptoms. A 75-year-old male patient presented to Al-zahra Clinic with diffuse abdominal pain. An abdominal surgery wa...

fibromatosis is the non-malignant proliferation of fibroblasts that aggressively invade adjacent tissues. it is composed of well-differentiated cells separated by considerable collagen and/or reticulin. the cause of this abundant growth is unknown, but many suspect hormonal or traumatic influences. when fibromatosis develops in the temporomandibular joint (tmj) or adjoining tissues, its aggress...

A silver colloid technique to identify nucleolar organiser region associated protein (AgNOR) was applied to 16 fibrous proliferations of childhood and six low grade fibrosarcomas. The fibrous proliferations comprised five cases of infantile digital fibromatosis, seven of infantile desmoid type fibromatosis, and four of infantile myofibromatosis. The AgNORs were visualised as dots within the nuc...

Fibromatosis encompasses a broad group of benign fibroblastic proliferations of similar microscopic appearance whose biologic behavior is intermediate between that of benign fibroblastic lesion and fibrosarcoma. Like fibrosarcoma, fibromatosis is characterized by infiltrative growth and frequent recurrences. But, unlike fibrosarcoma, fibromatosis never metastasizes. Fibromatosis can occur in va...

Desmoid tumor of the breast is a rare benign entity that usually is mistaken for carcinoma clinically and radiologically. We report two cases of desmoid tumor of the breast detected by mammography screening using digital breast tomosynthesis (DBT). The larger tumor was detected at both full-field digital mammography (FFDM) and DBT. The smaller desmoid tumor, however, was identified only at tomo...

Gastrointestinal Stromal Tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract and most commonly affects the stomach, while fibromatosis is a rare locally aggressive fibrous tissue neoplasm. There have been reports of GIST and fibromatosis occurring in same individual and in most of them fibromatosis occurs within the abdomen. In 75% of patients fibromatosis occurs aft...