The diffusion tensor is currently the accepted model of diffusion in biological tissues. The measured diffusion behavior may be more complex when two or more distinct tissues with different diffusion tensors occupy the same voxel. In this study, a partial volume model of MRI signal behavior for two diffusion-tensor compartments is presented. Simulations using this model demonstrate that the con...

A novel approach to reconstructing the principal directions of a diffusion tensor field directly from magnetic resonance imaging (MRI) data using a tensor tomography data acquisition approach was developed. If tensor eigenvalues are assumed to be known, the reconstruction of principal directions requires fewer measurements than the reconstruction of the full tensor field. The tensor tomography ...

We provide scientific background information and personal accounts relating to our publication of "Microstructural and Physiological Features of Tissues Elucidated by Quantitative-Diffusion-Tensor MRI" in the Journal of Magnetic Resonance B. This paper provided a framework for measuring and mapping intrinsic features of diffusion anisotropy obtained from diffusion tensor MRI (DTI) data.

This preprint is made available because the published work cited below had several infelicities due to production error, i.e., awkward layout of equations and font styles. The conversion from the Words document here to IEEE TMI format was a mess. Abstract An analytical framework of error propagation for diffusion tensor imaging (DTI) is presented. Using this framework, any uncertainty of intere...

1 Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland 2 Department of Diagnostics, Faculty of Medicine, University of Oulu, Oulu, Finland 3 Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland 4 Division of Brain Sciences, Academic Department of Neuro-otology, Imperial College London, Charing Cross Hospital Campus, London, UK *Corr...