Introduction: Cauda equina secondary to metastatic follicular thyroid cancer of the lumbosacral area is a rare entity.   Case Report: We report an unusual case of a 52-year-old male who presented with backache, lower limb weakness, and perianal numbness. A CT-scan of the lumbosacral area showed an enhancing mass at the L4, L5 and S1 vertebrae. Histopathology after excision revealed a metast...

Thyroid cancer is the commonest endocrine malignancy but represents only 1% of all cancers. Although the prognosis of differentiated thyroid cancer is good, the survival time of anaplastic and of medullary thyroid cancer is still very short. More precise diagnosis with better stratification of patients and identification of risk patients may improve the prognosis of thyroid cancer. Treatment of...

Prof. YJ Park, deputy editor of ‘Endocrinology and Metabolism,’ wrote a review on the prevalence of, and risk factors for, subclinical thyroid disease in Korea; this analysis was particularly clear [1]. Several review articles on thyroid cancer appeared in the third issue of 2014: “Molecular pathogenesis and targeted therapies in well-differentiated thyroid carcinoma”; “Current status and futur...

background: x-ray repair cross-complementing group 1 (xrcc1) gene is a dna repair gene and its non-synonymous single nucleotide polymorphisms (snp) may influence dna repair capacity which has been considered as a modifying risk factor for cancer development. methods: a case-control study was conducted to investigate impact of three frequently studied polymorphisms (arg194trp, arg280his and arg3...

Recombinant human TSH (rhTSH) brought revolutionary change in the management of patients with differentiated thyroid cancer since it was first approved for clinical use in the United States and Europe. Follow-up management of differentiated thyroid cancer is based on the detection of recurrent or residual cancer, traditionally achieved by measurement of serum thyroglobulin level and various ima...

The transformation of endodermal-derived thyroid follicular cells or neural crest– derived thyroid C cells leads to distinct types of cancer (Fig. 1). Follicular cells give rise to two main forms of differentiated thyroid cancer: papillary thyroid carcinoma and follicular thyroid carcinoma. Poorly differentiated and anaplastic thyroid carcinomas are comparatively rare tumors that also arise fro...

Thyroid cancer is among the most common endocrine malignancies. Genetic and environmental factors play an important role in the pathogenesis of differentiated thyroid cancer. Both have good prognosis but with frequent recurrences. Cancer staging is an essential prognostic part of cancer management. There are multiple controversies in the management and followup of differentiated thyroid cancer....

conclusions: this study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal i-131 accumulation in whole-body i-131 imaging. introduction: radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. differentiated thyroid cancers have the ability to trap iodine. therefore, rad...