To test a two-step approach for radioimmunotargeting of renal cell cancer, quadroma cells secreting antichelate X anti-renal cell carcinoma bispecific antibodies were obtained by somatic cell fusion. Five monoclo­ nal antibodies against the chelate l,4,7-triazaheptane-A^N',/V"-pentaacetic acid (DTPA) were produced and characterized. Competitive binding assays indicated that the anti-DTPA antibo...

To test a two-step approach for radioimmunotargeting of renal cell cancer, quadroma cells secreting antichelate x anti-renal cell carcinoma bispecific antibodies were obtained by somatic cell fusion. Five monoclonal antibodies against the chelate 1,4,7-triazaheptane-N,N',N"-pentaacetic acid (DTPA) were produced and characterized. Competitive binding assays indicated that the anti-DTPA antibodie...

BACKGROUND AND PURPOSE The complete removal of the stone is the ultimate goal in management, a result that might not be attained even after several sessions of percutaneous nephrolithotomy (PCNL) and/or extracorporeal shockwave lithotripsy (SWL) and/or retrograde intrarenal surgery (ureteroscopy). The objective of this study is to assess our technique of anatrophic nephrolithotomy, with decreas...

The objective of this study was to design and prepare a new contrast agent of magnetic resonance (MR) imaging for the evaluation of therapeutic angiogenesis. Diethylenetriaminepentaacetic acid (DTPA) residue of a chelator was chemically introduced to dextran with a molecular weight of 74,000 (dextran-DTPA). Cyclic peptide containing an arginine-glycine-aspartic acid (RGD) sequence (cyclic RGD) ...

BACKGROUND The newly developed magnetic-resonance-imaging (MRI) hepatocyte-specific contrast agent, gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA), has different excretion pathways from the conventional MRI contrast agent, gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). In this study, we compare the enhancement effect of the liver and renal parenchyma betwee...

Pseudomonas aeruginosa, a Gram-negative bacterium of clinical significance, produces elastase as a predominant exoprotease. Here, we screened a library of chemical compounds currently used for human medication and identified diethylene triamine penta-acetic acid (DTPA, pentetic acid) as an agent that suppresses the production of elastase. Elastase activity found in the prototype P. aeruginosa s...

In the presented work, possibility of direct synthesis LDH (layered double hydroxide) on AZ91 surface in presence a chelating agent (diethylenetriaminepentaacetic acid - DTPA) is reported. Conversion layer nanocontainers were formed under ambient pressure conditions without carbonate addition electrolyte. The obtained was characterized using experimental (SEM, XRD, TGA, XPS, Raman, etc.) and co...

A chelating agent helps crops to reuse as nutrients by mobilizing salts from the soil. This study was conducted evaluate effects of Diethylenetriamine pentaacetic acid (DTPA), N-(2-hydroxyethyl)-ethylene diaminetriacetic (HEDTA), and Ethylene diamine disuccininc (EDDS) for improving plant growth reusing accumulated in soils plastic film house. Two experiments were carried out follows: i) For in...

As technology is scaled down to 5 nm or even smaller, ruthenium (Ru) will most likely be chosen as the next generation barrier material for copper interconnects in integrated circuits (ICs). Recently, higher removal rate of Ru materials chemical mechanical polishing (CMP) has become a major issue. In this paper, diethylene triaminepentaacetic acid pentapotassium salt (DTPA-5K) was introduced ne...