BACKGROUND In this study, the presence of resistance to diclazuril, amprolium+ethopabate and salinomycin, representing some of the commonest anticoccidials in Iran's poultry industry, against three mixed Eimeria field isolates were investigated. METHODS Three Eimeria field isolates, collected from typical broiler farms in Iran, were propagated once, inoculated to 480 broilers, comprising 30 c...

Equine protozoal myeloencephalitis (EPM) is a nervous system disease caused by the protozoan Sarcocystis neurona. The clinical syndrome caused by the disease can have a variety of presentations. Classically, horses present with asymmetric ataxia and weakness defined by multifocal central nervous system lesions. Successful management of this disease has been frustrated by failure of treatment su...

The experiment was carried out with 150 Cobb broiler chickens divided into 3 groups with 50 birds each. The groups of infected chickens orally received 1ml of inoculum containing 3x10 3 Eimeria acervulina sporulated oocysts at 12 days of age. Group 1 was kept as a positive control with infected non-medicated birds, group 2 was medicated with diclazuril (1%) with a dose of 1mL/4 L of drinking wa...

Coccidiostats are authorized in the European Union (EU) to be used as poultry feed additives. Maximum (residue) levels (M(R)Ls) have been set within the EU for consumer and animal protection against unintended carry-over, and monitoring is compulsory. This paper describes the single-laboratory validation of a previously developed multiplex flow cytometric immunoassay (FCIA) as screening method ...

coccidiosis is a common disease of poultry breeding industry in the world that cause by eimeria spp. objective of the present study was comparison of anticoccidial effect of diclazuril and toltrazuril and their effects on the breeding function and intestinal oocyst shedding rate. therefore, 300 broilers from ross breed with 47 gr weigth average were divided into 3 groups randomely. then chicken...

Background: Coccidiosis is recognized as the parasitic disease that has the greatest economic impact on poultry production. Modern poultry production is largely dependent upon anticoccidials. Objectives: The aim of the present study was to determine and compare the efficacy of two chemical anticoccidials (Clopidol and Diclazuril) on oocyst shedding and their probable effects on growth performan...

This pilot study suggests that diclazuril and toltrazuril are absorbed after oral administration and have longer (40–55 h) plasma half-lives. These kinetic characteristics suggest readily maintained steady-state plasma concentrations. These are useful characteristics for therapeutic agents; however, therapeutic specifics for these agests in the horse remain to be determined. Authors’ address: M...

The current study assessed the anticoccidial efficacy of chitosan nanoencapsulated bromelain (CNB) against coccidiosis in goats. Bromelain was extracted from pineapple peels using standard methods while oral solution CNB prepared manufacturing methods. vivo done on fifteen healthy male goats naturally infected with coccidia. were divided into three groups consisting treatment (90 and 270 mg/Kg ...