in the near future, design of a new generation of drugs targeting proteins will be required. considering the complex bond between the drug and protein, the structure and stability of the target protein should be considered. so far, a series of in vitro investigations have been conducted with the aim of predicting drug-biological medium interactions. in these studies, use of spectroscopic method...

Intramolecular folding in three tandem guanine repeats of human telomeric DNA has been investigated using opticaltweezers, MD simulation and circular dichroism. A mechanically and thermodynamically stable species in this sequence shows a structure consistent with a triplex conformation. A similar species has also been observed to coexist with a G-quadruplex in a DNA sequence with four tandem gu...

The absorption and circular dichroism spectra of the intercalation complexes with DNA of the 9-aminoacridine chromophore in monoand bisfunctional forms have been determined in the visible/near-ultraviolet region. The experimental spectra were deconvoluted into contributions from three (It*, n) transitions and the dipole and rotatory strengths of one long-axis and one shortaxis polarized transit...

The orbital g-factor and the spin-orbit splittings of the first excited state of F-centres are measured in NaCl, NaBr, KBr and KF crystals by observing absorption and magnetic circular dichroism at various temperatures and using the moments method. Our experimental results and others are compared with Harker’s theoretical values. LE JOURNAL DE PHYSIQUE TOME 38, OCTOBRE 1977, Classification Phys...

We present an x-ray spectromicroscopic investigation of single-crystalline magnetic FeMn/Co bilayers on Cu 001 , using x-ray magnetic circular dichroism and x-ray magnetic linear dichroism XMLD at the Co and Fe L3 absorption edges in combination with photoelectron emission microscopy. Using the magnetic coupling between the ferromagnetic Co layer and the antiferromagnetic FeMn layer, we are abl...

The effects of YBa2Cu3O72d ~YBCO! cap layers on the magnetic and electronic properties of La0.7Sr0.3MnO3 ~LSMO! underlayers was determined by x-ray magnetic circular dichroism and x-ray absorption spectroscopy techniques. The YBCO caps alter the LSMO in a way that effectively decreases the concentration of La at the LSMO/YBCO interface. © 2000 American Institute of Physics. @S0021-8979~00!62908-0#