1. the most important challenge in diagnosis of celiac disease is not-performing the diagnostic tests in suspected persons. because of multi-organ damage and multiple manifestations of disease, diagnosis of celiac disease may be delayed. it seems general physicians should be aware about uncommon presentations of disease and indications of celiac tests. 2. the second most important challenge is ...

echocardiography plays a fundamental role in the evaluation of patients with an intracardiac mass. the ability to distinguish tissue characteristics, location, attachment, shape, size, and mobility non-invasively, quickly, and without the use of ionizing radiation makes echocardiography the ideal diagnostic modality. with careful attention to mass location and morphology, and appropriate applic...

bladder cancer is the fifth most common cancer with significant morbidity and mortality. recently, numerous studies demonstrated that micrornas are emerging as diagnostic biomarkers for bladder cancer. specific mirna profiles have been identified for several samples from patients with bladder cancer. micrornas are noncoding rna molecules of approximately 23 nucleotides that play important roles...

background: dna extraction is one the most important steps for molecular analysis of food-borne pathogens. in this research, three methods of dna extractions from beef harboring sarcocystis spp. were compared for the quality, quantity, safety, as well as cost-effectiveness. methods: about 100 mg intersostal and diaphragm were collected from 10 slaughtered cattle. after ensuring their contaminat...

error is an inevitable part of life and cannot be completely eliminated, but it can be minimized. a root cause analysis is a technique for understanding the systematic error causes that is involved beyond a person or people to implement an errors and including field and environmental causes of errors when occur in this situation too. an important factor of an error occurrence is a root cause (c...

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currently, different highly sensitive nucleic acid detection-based protocols used in medical diagnostic laboratories need specific working conditions, and if no optimization is performed, misleading results can be obtained. limitations of each protocol is different in obtaining an appropriate result. awareness of these limitations plays an important role in providing a reliable result for physi...