Abstract Diabetic retinopathy is a neurovascular complication of diabetes which an avoidable cause sight loss. Since the introduction screening for diabetic in UK along with improving treatments both and it no longer leading blindness UK. Screening detects at early stage when optimisation blood glucose, pressure cholesterol are effective reducing progression retinopathy. Once proliferative or m...

background: type 2 diabetic mellitus patients are amongst the most susceptible groups to vascular abnormalities, which predominantly lead to myocardial disease. the hypercoagulable state has been widely studied by researchers as being the major suspicious mechanism facilitating the consecutive chain of molecular events leading to these complications. however, there is no consensus on the defini...

a 33-year-old female-a known case of behcet's disease- was admitted to the hospital due to fever, dyspnea and hemoptysis. one week before admission, she had developed right leg swelling. the history suggested either deep vein thrombosis (dvt) and pulmonary emboli or pulmonary artery vasculitis. diagnostic tests were requested and the necessary treatment was started accordingly

Earlier Diabetic nephropathy was thought to be a rare complication in Type II Diabetic patients. The incidence and prevalence of nephropathy in Type II Diabetes have been under estimated in the past probably because most patients with nephropathy succumbed to cardiovascular disease, even before nephropathy could manifest clinically. The current study was done to screen Type II diabetic patients...

Diabetic retinopathy is a common complication of diabetes and remains the leading cause of blindness among the working-age population. For decades, diabetic retinopathy was considered only a microvascular complication, but the retinal microvasculature is intimately associated with and governed by neurons and glia, which are affected even prior to clinically detectable vascular lesions. While pr...

BACKGROUND Diabetic nephropathy (DN) is a serious vascular complication of diabetes and an important cause of end-stage renal disease. One mechanism by which hyperglycemia causes nephropathy is through the formation of advanced glycation end products (AGE). Development of vaccination would be a promising therapy for the future, while to date, anti-AGE therapy is based on medicines that are need...

Abstract Background and aims Diabetic peripheral neuropathy (DPN) is a common microvascular complication in type 2 diabetes mellitus (T2DM). The nerve fibers injury caused by the interaction between metabolic vascular factors. Vascular endothelial growth factor (VEGF) an essential for cells. We aimed to investigate relation VEGF-A serum level degree of DPN. Results This cross-sectional study wa...

Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss...

Diabetic retinopathy, the most frequent complication of diabetes and leading cause of vision loss, involves vascular and neural damage in the retina. Insulin and IGF-1 signaling are now shown to contribute to retinal neovascularization, in part, by modulating the expression of various vascular mediators.