background: sustainable and commercial production of secondary metabolites is a critical issue when dealing with its clinical application. efforts are still being made to look for biotic or abiotic elicitors with more efficient and universal effects on the improvement of secondary metabolites. objective: in order to evaluate the suitability of different biotic elicitors on p. harmala l. cell su...

introduction: inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary. the use of cell culture-based vaccine production is one way of overcoming the limitations of the egg-based method and securing a more rapid re...

zinc and iron nano-oxides (100 ppb) were promoted the hypericin and hyperforin production in hypericum perforatum cell suspension culture. high performance liquid chromatography method was used for detectection and identification of hypericin and hyperforin in h. perfuratum cell suspension cultures elicited with different concentrations of zinc and iron nano-oxide (0, 50, 100 and 150 ppb) after...

Natural-based drugs are the important bioactive substances that have been used for prevention and treatment of diseases. Natural products should be prepared in commercial scale from relevant medicinal plants. Hence, large amounts of the plants have been needed for extraction and isolation of compounds of natural origin. Plant cells technology is the best strategy for the production of the plant...

introduction: stromal cells having preadipocyte characteristics can be isolated from adipose tissue, propagated in vitro and induced to differentiate in vitro toward the osteogenic, adipogenic, myogenic and chondrogenic lineages when treated with established lineage-specific factors. in this research we isolated stromal cells from human adipose tissue and cultured and expanded and examined thei...

background: adipose derived stem cells (ascs) provoke the accumulation and expansion of regulatory t cells, leading to the modulation of immune responses in tumor microenvironment. objective: to assess the effect of tumoral ascs on the trend of regulatory t cells differentiation. methods: peripheral blood naïve cd4+ t cells were co-cultured with ascs derived from breast cancer or normal breast ...

conclusions this review was to focus on the roles of ascs in different applications and also provide the researcher general information about the history and current applications of ascs. we found that the ascs have a potential role to be used for the treatment of different sorts of disorders, with the less side effects and is also a new approach toward new remedies. context after about 40 year...

cell cultures of varthemia persica dc. have been studied to evaluate their abilities in biotransformation of aromatic and aliphatic precursors. v. persica (asteraceae) is an aromatic plant growing in iran. v. persica contain different terpens but its cell culture does not posses these compounds. callus cultures of v. persica was established from seedlings and healthy suspensions were grown usin...