Synthesis of palynucleotides has been in progress in our laboratory for the last ten years. Chemically synthesized deoxyribo-oligonucleotides of well defined size and structure have served as substrates to elucidate the mode of action of a number of enzymes which degrade nucleic acids; e.g., spleen phasphadiesterase and venom phosphodiesterase. They have also been used as models to develop chem...

In today’s era as the rate of information storage and transformation is growing day by day; so as information security is becoming more important. To provide security to information there are various types of techniques as traditional cryptographic methods like Substitution techniques, Transposition techniques, hashing Functions and algorithms like DES , RSA, AES, IDEA, ECC etc. are used. DNA c...

Hemoglobinopathy refers to a disease involving qualitative or quantitative defect of the structure synthesis haemoglobin molecules. The HaemoglobinS- beta thalassemia occurs in heterozygotes individual with beta-thalassemia and HaemoglobinS gene. A 29-year-old man came severe anemia, thrombocytopenia, history repeated blood transfusions. Physical examination showed pale conjunctiva, pansystolic...

Since security is one of the most important issues, the evolvement of cryptography and cryptographic analysis are considered as the fields of on-going research. The latest development on this field is DNA cryptography. It has emerged after the disclosure of computational ability of Deoxyribo Nucleic Acid (DNA). DNA cryptography uses DNA as the computational tool along with several molecular tec...

uses of ailcylating reagents (1, 10) including those derived from the sulfur and nitrogen mustard gases, is the occasion for the publication of the details of an investigation conducted between 1943 and 1946 in the Department of Chemistry of New York University College of Medicine under a contract with OSRD (OEM8r1O5O). The material has been set forth in a final report (OSRD No. 6665) which has...

Cancer is a condition arising from the deregulation of several genes which causes change in normal cells to cancerous ones. The objective all cancer treatment research eradicate with little effect on cells. Nanostructured ceria very small dimension (≈5nm) synthesized by co-precipitation method using deoxyribo nucleic acid (DNA) as capping agent has shown promising antioxidant activity over almo...

background nucleic acid based detection of mycobacterium tuberculosis has the potential to improve the analysis of the tuberculosis epidemiology and patient care by increasing the specificity and sensitivity of diagnosis. patients and methods fifty suspected cases were screened for m. tuberculosis by using a new primer sequence and comparing its results with the primer (is6110) most widely used...

cytotoxicity evaluation of daphne mucronata (thymelaeaceae) extract and one of its active purified components, using seven different cancerous cell lines, revealed the strong antiproliferative activity of the plant. using flow cytometry technique, it was found that treatment of the most responsive cells (k562) with the plant extract or the active component inhibited the progression of cells thr...