Objective(s):Growing evidence indicates that extract of Ginkgo biloba (EGb) attenuates hippocampal-dependent memory deficit in aged individuals; however, very little is known about the effect of EGb on the structure of hippocampus. Therefore we examined the EGb-induced morphological changes of the Cornu Ammonis (CA) region in aged rats. Materials and Methods: Sixteen aged male Wistar rats, 24 ...

In the present study, the corrosion behavior of AISI 347 austenitic stainless steel to ASTM A335 low alloy steel dissimilar joint was investigated. For this purpose, two filler metals, ER309L and ERNiCr-3, were selected to be used during the gas tungsten arc welding process. To investigate the corrosion behavior of the joints after welding, the specimens were tested in 3.5% sodium chloride solu...

background and aims: this study examined sub-chronic effects of methamphetamine (meth) on the stereological parameters in the cornu ammonis (ca) of the hippocampus in adult mice. materials and methods: fifteen adult male mice, eight weeks old, were randomly divided into three groups: receive saline (controls), or low-dose (ld) 2.5 mg/kg meth, or high-dose (hd) 25 mg/kg meth, via daily intraperi...

background: dendritic cells (dcs) are professional antigen presenting cells that have an important role in the initiation of immune response. the use of maturation factors in dendritic cell differentiation provides a promising approach in immunotherapy. objective: in this study, we compared tumor necrosis factor-α, polyribocytidylic acid, lipopolysacharide and cpg oligonucleotides in inducing d...

Introduction: Ovarian hyper-stimulation is widely used in IVF clinics. The main purpose of this method is to stimulate folliculogenesis and increase the number of oocytes in one cycle. Following ovarian hyper-stimulation, hormonal secretion of the ovary, particularly estradiol and progesterone dramatically increases. Immune cells especially dendritic cells have receptors for the estradiol...

Activity-dependent changes in synaptic structure and spine morphology are required for learning and memory, and depend on protein translation. We show that the kinase for eukaryotic elongation factor 2 (eEF2K) regulates dendritic spine stability and synaptic structure by modulating activity-dependent dendritic BDNF synthesis. Specifically RNAi knockdown of eEF2K reduces dendritic spine stabilit...