apoptosis is chromosomal DNA degradation by deoxyribonuclease (DNase)-mediated fragmentation. In mammals, these DNases include DNA fragmentation factor 40 kDa (DFF40) and its chaperone and inhibitor, DFF45. During apoptosis, caspases cleave DFF45, releasing DFF40 to cleave DNA. In Caenorhabditis elegans, however, no homologues of DFF40 and DFF45 have been identified, and it is unclear how apopt...

The aim of the study was to compare the outcome of external DCR with and without stenting with silicon tube and analyse the results of silicon intubation whether it improves the overall success rate of DCR. Success rate for external DCR without STI was 80% in our study .Success rate for DCR with STI rose to 92%.Therefore DCR with STI is a highly successful procedure with a success rate of over ...

PURPOSE Specular images of the tear film in the central cornea were examined in patients with nasolacrimal duct obstruction to observe changes before and after dacryocystorhinostomy (DCR). METHODS We observed the specular images in 4 patients (5 eyes) by a noncontact observation device and recording system. Observed patterns were classified into five grades. The specular images and tear menis...

PURPOSE External and endonasal dacryocystorhinostomy (EX-DCR and EN-DCR, respectively) affect the tear drainage mechanism. This study evaluates the preservation of "lacrimal pump" function in both procedures. METHODS Cases of successful EN-DCR (4 patients) and EX-DCR (4 patients) were included. All patients underwent MRI of the rhinostomy areas, at least 6 months postoperatively. The vertical...

We study modularity, run-time adaptation and refinement under safety and liveness constraints in event-based process models with dynamic sub-process instantiation. The study is part of a larger programme to provide semantically well-founded technologies for modelling, implementation and verification of flexible, run-time adaptable processaware information systems, moved into practice via the Dy...

When the control unit detects the diagnose input sequence, it sets the DCR (p, = 1 for all 0, and drives the architecture to the DTM by setting NIT = 0 and TID = 0. This switches the MUX driving To,, to the DCR output therefore driving the external output to a logic 1, to signal that the device is in DTM (see Fig. 2). The control unit then sets the DCR to the shift mode, starting a partition id...

MicroRNAs (miRNAs) regulate gene expression by controlling the turnover, translation, or both of specific mRNAs. In Drosophila, Dicer-1 (Dcr-1) is essential for generating mature miRNAs from their corresponding precursors. Because miRNAs are known to modulate developmental events, such as cell fate determination and maintenance in many species, we investigated whether a lack of Dcr-1 would affe...

BACKGROUND To compare the capability of lung nodule detection and characterization between dual-energy radiography with color-representation (DCR) and conventional gray scale chest radiography (GSR). METHODS A total of 130 paired chest radiographs (DCR and GSR) obtained from 65 patients (14 with normal scans and 51 with pulmonary nodules) were evaluated. After analysis, 45 non-calcified and 2...