نتایج جستجو برای: dcm

تعداد نتایج: 3188  

Journal: :FEMS microbiology letters 2014
Kevin T Militello Alexandra H Mandarano Olga Varechtchouk Robert D Simon

Escherichia coli K-12 strains contain the orphan cytosine-5 DNA methyltransferase enzyme Dcm (DNA cytosine methyltransferase). Two recent reports indicate that Dcm has an influence on stationary phase gene expression in E. coli. Herein, we demonstrate that dcm knockout cells overexpress the drug resistance transporter SugE, which has been linked to ethidium bromide (ETBR) resistance. SugE expre...

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Journal: :Microbiology 2000
G J Evans G P Ferguson I R Booth S Vuilleumier

Dichloromethane (DCM) dehalogenase converts DCM to formaldehyde via the formation of glutathione metabolites and generates 2 mol HCl per mol DCM metabolized. Growth of Escherichia coli expressing DCM dehalogenase was immediately and severely inhibited during conversion of 0.3 mM DCM. Intracellular pH (pH(i)) rapidly decreased and chloride ions were steadily released into the medium. Bacterial g...

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2016
Domenico Tricò Simona Baldi Silvia Frascerra Elena Venturi Paolo Marraccini Danilo Neglia Andrea Natali

Dilated cardiomyopathy (DCM) is characterized by a metabolic shift from fat to carbohydrates and failure to increase myocardial glucose uptake in response to workload increments. We verified whether this pattern is influenced by an abnormal glucose tolerance (AGT). In 10 patients with DCM, 5 with normal glucose tolerance (DCM-NGT) and 5 with AGT (DCM-AGT), and 5 non-DCM subjects with AGT (N-AGT...

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Journal: The Iranian Journal of Pharmaceutical Research 2018
Abbas Delazar, Elmira zolali, Fariba Heshmati Afshar, Haleh Vaez, Parina Asgharian, Solmaz Asnaashari,

Scrophularia genus belonging to the family of Scrophulariaceae, is a medicinal plant widely distributed in Iran. In the present study,the anti-malarial activity of different extracts of three Iranian endemic species of Scrophularia including S. frigida, S. subaphylla and S. atropatana, was screened by an in-vitro preliminary assay. The plant materials were extracted successively with n-hexane, ...

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2015
Robert H Lurie

Additional Acknowledgements Magnetic resonance imaging work was performed at the Northwestern University Center for Advanced Molecular Imaging generously supported by NCI CCSG P30 CA060553 awarded to the Robert H Lurie Comprehensive Cancer Center. Metal analysis was performed at the Northwestern University Quantitative Bioelemental Imaging Center generously supported by NASA Ames Research Cente...

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2011
Karl J. Friston Baojuan Li Jean Daunizeau Klaas E. Stephan

This paper is about inferring or discovering the functional architecture of distributed systems using Dynamic Causal Modelling (DCM). We describe a scheme that recovers the (dynamic) Bayesian dependency graph (connections in a network) using observed network activity. This network discovery uses Bayesian model selection to identify the sparsity structure (absence of edges or connections) in a g...

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Journal: :iranian journal of radiology 0
ling-yi wen department of radiology, west china hospital, sichuan university, chengdu, china zhi-gang yang department of radiology, west china hospital, sichuan university, chengdu, china; national key laboratory of biotherapy, west china hospital, sichuan university, chengdu, china; department of radiology, west china hospital, sichuan university, chengdu, china. tel/fax: +86-28 85423817 ying-kun guo department of medical imaging, west china second university hospital, sichuan university, chengdu, china jia-yu sun department of radiology, west china hospital, sichuan university, chengdu, china hua-yan xu department of radiology, west china hospital, sichuan university, chengdu, china; national key laboratory of biotherapy, west china hospital, sichuan university, chengdu, china

results of the 41 patients with dcm, echocardiography examination revealed 11 patients (27%) without mitral regurgitation and 12 (29%) with mild, 11 (27%) with moderate, and seven (17%) with severe mitral regurgitation. all of the morphological and functional parameters of left ventricle, atrium and mitral valve in dcm patients were greater than those in healthy subjects (all p < 0.05), except ...

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Journal: :NeuroImage 2011

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2015
Lauren A. Cole Jonathan H. Dennis P. Bryant Chase

β-adrenergic signaling pathways mediate key aspects of cardiac function. Its dysregulation is associated with a range of cardiac diseases, including dilated cardiomyopathy (DCM). Previously, we established an iPSC model of familial DCM from patients with a mutation in TNNT2, a sarcomeric protein. Here, we found that the β-adrenergic agonist isoproterenol induced mature β-adrenergic signaling in...

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Journal: :Journal of the American College of Cardiology 2003
Matthew R G Taylor Pamela R Fain Gianfranco Sinagra Misi L Robinson Alastair D Robertson Elisa Carniel Andrea Di Lenarda Teresa J Bohlmeyer Debra A Ferguson Gary L Brodsky Mark M Boucek Jean Lascor Andrew C Moss Wai Lun P Li Gary L Stetler Francesco Muntoni Michael R Bristow Luisa Mestroni

OBJECTIVES We examined the prevalence, genotype-phenotype correlation, and natural history of lamin A/C gene (LMNA) mutations in subjects with dilated cardiomyopathy (DCM). BACKGROUND Mutations in LMNA have been found in patients with DCM with familial conduction defects and muscular dystrophy, but the clinical spectrum, prognosis, and clinical relevance of laminopathies in DCM are unknown. ...

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