Wei Qing Ong 1,*, Alan Wee Chiat Tan 1, V. Vijayakumar Vengadasalam 1, Cheah Heng Tan 2 and Thean Hai Ooi 2 1 Faculty of Engineering and Technology, Multimedia University, Jalan Ayer Keroh Lama, Melaka 75450, Malaysia; [email protected] (A.W.C.T.); [email protected] (V.V.V.) 2 Motorola Solutions Malaysia Sdn. Bhd., Plot 2 Technoplex Industrial Park, Mukim 12 SWD, Bayan Lepas, Penang 11900, Malay...

If you believe this document infringes copyright then please contact the KAR admin team with the take-down information provided at http://kar.kent.ac.uk/contact.html Citation for published version Singh, R P and Hillier, Adrian D and Mazidian, Bayan and Quintanilla, Jorge and Annett, James F and Paul, D McK and Balakrishnan, G and Lees, M R (2014) Detection of Time-Reversal Symmetry Breaking in...

A new parvicursorine alvarezsauroid theropod specimen IVPP V20341 from the Upper Cretaceous Wulansuhai Formation of Bayan Mandahu, Inner Mongolia, China is described. IVPP V20341 appears to be distinguishable amongst alvarezsauroids by possible cervical procoely and relatively larger semi-circular caudal neural canals, but these features are not proposed as autapomorphies because current knowle...

Darinaparsin (Dar; ZIO-101; S-dimethylarsino-glutathione) is a promising novel organic arsenical currently undergoing clinical studies in various malignancies. Dar consists of dimethylarsenic conjugated to glutathione (GSH). Dar induces more intracellular arsenic accumulation and more cell death than the FDA-approved arsenic trioxide (ATO) in vitro, but exhibits less systemic toxicity. Here, we...

BACKGROUND The development of a novel tuberculosis vaccine is a leading global health priority. SRL172, an inactivated, whole-cell mycobacterial vaccine, was safe, immunogenic and reduced the incidence of culture-confirmed tuberculosis in a phase III trial in HIV-infected and BCG immunized adults in Tanzania. Here we describe the immunogenicity and protective efficacy of DAR-901, a booster vacc...

The Roshnites (Illuminati) also called “Rokhanian” in Pashto, a sixteenth century religiopolitical movement in the Pashtun dominated regions of Pakistan and Afghanistan, effected social mobilization on an unprecedented scale. The movement aimed at doctrinal reforms but soon it turned out to be a political movement. The leader of the Movement, Bayazid Ansari (also called “Pir Rokhan” by his devo...

Previously, D2 dopamine receptors (D2 DARs) have been shown to undergo G-protein-coupled receptor kinase phosphorylation in an agonist-specific fashion. We have now investigated the ability of the second messenger-activated protein kinases, protein kinase A (PKA) and protein kinase C (PKC), to mediate phosphorylation and desensitization of the D2 DAR. HEK293T cells were transiently transfected ...

BACKGROUND Loss of dorsal acetabular rim (DAR) is a common sequela to canine hip dysplasia. The purpose of this study is to evaluate the effect of DAR loss on the initial stability of the cementless (BFX) acetabular cup. BFX cups were implanted into foam blocks reamed to resemble acetabulae with simulated 0, 25, 50, and 75% DAR loss. Models were tested in edge loading of the lateral surface of ...