Ethanolic extract of pomegranate (Punica granatum L) peel: acute toxicity tests on zebrafish (Danio rerio) embryos and its prediction by in silicoIndra Wibowo, Kurnia Permadi, Rika Hartati, Sophi Damayanti

Decisions about joining social groups are often contingent on one’s own phenotypic characteristics and those of existing group members. Zebrafish and their allies (genus Danio) vary substantially in the expression of conspicuous lateral stripes. We presented wild-type zebrafish (D. rerio), two artificially selected D. rerio strains with reduced stripe expression, as well as the stripeless D. al...

The evolutionary relationships of species of Danio and the monophyly and phylogenetic placement of the genus within the family Cyprinidae and subfamily Rasborinae provide fundamentally important phyloinformatics necessary for direct evaluations of an array of pertinent questions in modern comparative biology. Although the genus Danio is not one of the most diverse within the family, Danio rerio...

BACKGROUND Eukaryotic DNA polymerase β (pol β), the polymerase thought to be responsible for DNA repair synthesis, has been extensively characterized in rats and humans. However, pol β has not been purified or enzymatically characterized from the model fish species Danio rerio (zebrafish). We used the in vitro/in vivo dual expression system plasmid, pIVEX, to express Danio rerio pol β (Danio po...

Individual zebrafish Danio rerio were assayed for exploratory tendency in a serial open field test before and after being maintained on one of four diet treatments that differed in ration and in predictability of food delivery. Danio rerio became more exploratory after being maintained on a diet with a predictable delivery schedule. There was no effect of ration. Thus, exploratory behaviour is ...

In this study, we evaluated the bioaccumulation of mercury in zebrafish (Danio rerio) exposed to mercury-contaminated food for 21 days and depuration a subsequent post-exposure period 28 days. Four tissues (muscle, liver, gills, skin) were analyzed content. Overall, data indicated that Hg accumulation liver is faster than other tissues. Furthermore, tissue with highest rate per day (0.021 µg g−...

AGAT, GAMT and CT1, three creatine synthesis and transport-related molecules, have been widely studied in mammals. To explore their homologous genes in adult zebrafish Danio rerio, the gene expression patterns of these three genes in D. rerio were investigated. The results reveal that AGAT, GAMT and CT1 are expressed widely in diverse tissues of D. rerio where the homologous genes in mammals ar...

The zebrafish has long been a favourite model for the study of vertebrate development. Here we provide an overview of the current state of knowledge and resources for the study of this fish, with comments on the future direction of zebrafish genomics from Professor Mark Fishman and Dr Stephen Wilson.