نتایج جستجو برای: dalteparin

تعداد نتایج: 393  

Journal: :Annals of internal medicine 2013
David R Anderson Michael J Dunbar Eric R Bohm Etienne Belzile Susan R Kahn David Zukor William Fisher Wade Gofton Peter Gross Stephane Pelet Mark Crowther Steven MacDonald Paul Kim Susan Pleasance Nicki Davis Pantelis Andreou Philip Wells Michael Kovacs Marc A Rodger Tim Ramsay Marc Carrier Pascal-Andre Vendittoli

BACKGROUND The role of aspirin in thromboprophylaxis after total hip arthroplasty (THA) is controversial. OBJECTIVE To compare extended prophylaxis with aspirin and dalteparin for prevention of symptomatic venous thromboembolism (VTE) after THA. DESIGN Multicenter randomized, controlled trial with a noninferiority design based on a minimal clinically important difference of 2.0%. Randomizat...

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Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2009
M De Cicco M Matovic L Balestreri A Steffan R Pacenzia M Malafronte D Fantin C A Bertuzzi F Fabiani S Morassut E Bidoli A Veronesi

BACKGROUND We evaluated efficacy and safety of early and short-term prophylaxis with acenocumarine or dalteparin in the prevention of non-occlusive or occlusive central vein catheter-related thrombosis (CVCrT). PATIENTS AND METHODS Consecutive cancer patients scheduled for chemotherapy randomly received: acenocumarine 1 mg/day for 3 days before and 8 days after central vein catheter (CVC) ins...

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2010
KLAS NORRBY ARVID NORDENHEM

Tumors are angiogenesis dependent and vascular endothelial growth factor-A (VEGF-A), a heparin-binding protein, is a key angiogenic factor. As chemotherapy and co-treatment with anticoagulant low-molecular-weight heparin (LMWH) are common in cancer patients, we investigated whether angiogenesis in vivo mediated by VEGF-A is modulated by metronomic-type treatment with: (i) the LMWH dalteparin; (...

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Journal: :basic and clinical neuroscience 0
fereshteh farajdokht arezo nahavandi mansoureh soleimani

introduction: stress is defined as any environmental change that disturbs the maintenance of brain homeostasis. stress leads to production of pro-inflammatory cytokines that provoke neurodegenerative disorders. in the present study, we investigated the effects of dalteparin on hippocampal neuronal death induced by chronic stress in rats. methods: the study was carried out on 60 adult male wista...

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2009
OLIVERA M. BOSNIĆ KRISTINA R. GOPČEVIĆ MIROSLAV M. VRVIĆ IVANKA M. KARADŽIĆ

The interaction between trypsin, a prototype S1 serine protease, with heparin and its low molecular weight derivative dalteparin were investigated. Direct inhibition of the proteolytic activity of trypsin by heparin and dalteparin, used in concentrations typical for their clinical application, was detected. The half-maximum inhibition of the trypsin activity was achieved at 15.25±1.22 μg/mL for...

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Journal: :Canadian journal of surgery. Journal canadien de chirurgie 2009
Timothy H Bell Donna Berta Fiona Ralley Steven J Macdonald Richard W McCalden Robert B Bourne Cecil H Rorabeck Douglas D R Naudie

BACKGROUND: In recent years, the use of low molecular weight heparins such as dalteparin has become attractive because of their ease of administration and superiority in preventing venous thromboembolism (VTE) compared with traditional agents. The primary purpose of our study was to evaluate the impact of dalteparin use on blood loss and transfusion rates in patients undergoing primary total jo...

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2014
Yasuji Inamo Katsuya Saito Maki Hasegawa Rika Hayashi Takahiro Nakamura Osamu Abe Teruaki Ishikawa Yayoi Yoshino Koji Hashimoto Tatsuo Fuchigami

BACKGROUND Dalteparin, a low-molecular-weight heparin, has anticoagulant and anti-angiogenic activity. This study investigated whether dalteparin reduced coronary artery lesion (CAL) prevalence, and resistance to intravenous immunoglobulin (IVIG) therapy in Kawasaki disease (KD). METHODS This retrospective study comprised two parts. In the first cohort, 126 patients with KD (68 male, 58 femal...

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Journal: :Canadian family physician Medecin de famille canadien 2005
Ariel Many Gideon Koren

QUESTION A few years ago I suffered from pulmonary emboli. My physician recommended I use dalteparin during this pregnancy although, during my previous pregnancy, I had received subcutaneous heparin injections three times daily. Is dalteparin the same as heparin? ANSWER : Based on the best available evidence from mostly small prospective case series, retrospective reports, and placental perfu...

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Journal: :Blood 2001
R Storb G Sale T Barnett C Yu E Zellmer M T Little

pathologic hair loss or even alopecia, was noticed. In the other 4 patients, hair was coming out in handfuls, leaving large areas of mutilating patchy alopecia. Those 4 patients reported that hair loss had begun approximately 6 weeks to 3 months after initiation of hemodialysis. We suspected that repeated anticoagulation with dalteparin, which shares many side effects with heparin,4 was respons...

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Journal: :Diabetes care 2003
Majid Kalani Jan Apelqvist Margareta Blombäck Kerstin Brismar Björn Eliasson Jan W Eriksson Bengt Fagrell Anders Hamsten Ole Torffvit Gun Jörneskog

OBJECTIVE Chronic foot ulcers are a common, severe, and expensive complication threatening life and limb in patients with diabetes. The aim of the present study was to investigate the effect of dalteparin on ulcer outcome in patients with diabetes, peripheral arterial occlusive disease, and chronic foot ulcers. RESEARCH DESIGN AND METHODS A total of 87 patients were investigated in a prospect...

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