Abbreviations BI D bibliographic database; CA D catalogue of chemicals; db D database; DADB D metadatabase of online databases; DACD D metadatabase of CD-ROMs; DAIN D metadatabase of internet resources; FBDB D fact-based database; FT D fulltext database; INDB D integrated database; MD D metadatabase; NU D numeric database; RD D research database; RE D reaction database; ST D structural database...

The present study was designed to probe the effects of Huperzine A (HupA) on diabetes-associated cognitive decline (DACD) using a streptozotocin (STZ)-injected rat model. Diabetic rats were treated with HupA (0.05 and 0.1 mg/kg) for seven weeks. Memory functions were evaluated by the water maze test. Nissl staining was selected for detecting neuronal loss. Protein and mRNA levels of brain-deriv...

Our present investigation aimed to determine the neuroprotection of apigenin (API) against diabetes-associated cognitive decline (DACD) a diabetic rat model and exploring its potential mechanism. Diabetic rat model was induced by intraperitoneal injection of streptozotocin. All experiment animals treated with vehicle or API by doses of 10, 20 and 40 mg/kg for seven weeks. Firstly, the body weig...

OBJECTIVES Previous research demonstrated that diabetes is one of the leading causes of learning and memory deficits. Naringin, a bioflavonoid isolated from grapefruits and oranges, has potent protective effects on streptozotocin (STZ)-induced diabetic rats. Recently, the effects of naringin on learning and memory performances were monitored in many animal models of cognitive impairment. Howeve...

Cloud computing provides a service based on internet for several shared resources and system software across various environment. For secure cloud storage the process of encryption of the data to the users for various needs has been brought by the delegated access control method. Generally storage in public cloud requires high communication, heavy load due to maximum storage and high computatio...

Baicalin is an important active component of the medicinal herb Scutellaria baicalensis Georgi and has shown a variety of pharmacological actions. The present study aimed to evaluate the neuroprotective effects of baicalin against diabetes‑associated cognitive deficits (DACD) in rats and to elucidate the potential molecular mechanisms of action. A rat model of diabetes mellitus was prepared by ...

BACKGROUND To investigate the effects of treatment with Multi component Chinese Medicine Jinzhida (JZD) on behavioral deficits in diabetes-associated cognitive decline (DACD) rats and verify our hypothesis that JZD treatment improves cognitive function by suppressing the endoplasmic reticulum stress (ERS) and improving insulin signaling transduction in the rats' hippocampus. METHODS A rat mod...

Objective(s):Previous research demonstrated that diabetes is one of the leading causes of learning and memory deficits. Naringin, a bioflavonoid isolated from grapefruits and oranges, has potent protective effects on streptozotocin (STZ)-induced diabetic rats. Recently, the effects of naringin on learning and memory performances were monitored in many animal models of cognitive impairment. Howev...

Given a large network and a query node, finding its top-k similar nodes is a primitive operation in many graphbased applications. Recently enhancing search results with diversification have received much attention. In this paper, we explore an novel problem of searching for top-k diversified similar nodes in attributed networks, with the motivation that modeling diversification in an attributed...