BACKGROUND A knowledge-based radiation therapy (KBRT) treatment planning algorithm was recently developed. The purpose of this work is to investigate how plans that are generated with the objective KBRT approach compare to those that rely on the judgment of the experienced planner. METHODS Thirty volumetric modulated arc therapy plans were randomly selected from a database of prostate plans t...

BACKGROUND Dexamethasone (Dex) limits and all-trans-retinoic acid (RA) promotes alveolarization. While structural changes resulting from such hormonal exposures are known, their functional consequences are unclear. METHODS Neonatal rats were treated with Dex and/or RA during the first two weeks of life or were given RA after previous exposure to Dex. Morphology was assessed by light microscop...

Through the interaction of T follicular helper (Tfh) cells and B cells, efficacious vaccines can generate high-affinity, pathogen-neutralizing antibodies, and memory B cells. Using CXCR5, CXCR3, CCR6, CCR7, PD1, and ICOS as markers, Tfh-like cells can be identified in the circulation and be classified into three functionally distinct subsets that are PD1+ICOS+, PD1+ ICOS-, or PD1-ICOS-. We used...

Se evaluó el uso de las reservas energéticas reproductores juveniles Pteria sterna (50 mm altura; 9 meses edad) durante su primera madurez sexual en condiciones laboratorio. empleó una dieta microalgal base (Dieta M) complementada con fécula maíz rica carbohidratos (dietas F1 y F2) microcápsulas ricas lípidos L1 L2), equivalente a ración diaria del 1 2 % la biomasa seca tejidos blandos. hiciero...

Resumo: Introdução: A comunicação é intrínseca ao ser humano e necessária para a prática médica. Comunicar más notícias uma das tarefas mais difíceis impostas aos médicos, o aprendizado dessa habilidade deve fazer parte do ensino médico. O de desde graduação Objetivo: Este estudo teve como objetivos avaliar qualidade da estudantes Medicina submetidos cenários simulados com paciente padronizado ...

INTRODUCTION As important effector cells of the innate immune system, neutrophils are involved in rejection of solid organ and/or tissue transplants. But their role in rejection of oral mucosa transplantation (OMT) remains unclear. The aim of this study is to observe the spatial-temporal change of neutrophils during acute rejection of OMT. METHODS In a rat model of oral mucosal xenotransplant...

Silicone oil (SiO) and fluorosilicone oil (FSiO) are useful in difficult cases of retinal detachment surgery. Unidentified low-molecular-weight components (LMWC) and residual catalysts in SiO and FSiO have been implicated in the adverse reactions of the oils in the eye. The authors analyzed LMWC of SiO and FSiO using a gas chromatograph (GC) equipped with a 6-ft x 2-mm column packed with 3% SP-...

The Rh D blood-group antigen forms part of a complex, involving several other polypeptides, that is deficient in the red cells of individuals who lack all the antigens of the Rh blood-group system (Rhnull red cells). These include components recognized by anti-(Rh D) antibodies and the murine monoclonal antibodies R6A and BRIC 125. We have carried out protein-sequence studies on the components ...

OBJECTIVE To study whether effect of aspirin plus low-dose diethylstilbestrol is more effective and safer than high diethylstilbestrol dose alone on prevention of ovariectomy-induced osteopenia and dyslipidemia. METHODS Thirty-eight 4-month-old female SD rats were divided into baseline (BAS) group (n=6), sham operation group (n=8) and ovariectomy (OVX) group (n=24). The OVX group was further ...

Transarterial chemoembolization (TACE) has therapeutic effects in patients with unresectable hepatocellular carcinoma (HCC), but its impact on the cellular immune response during disease progression is largely unknown. Here we conducted a prospective study to evaluate the effect of TACE on immune status and to identify prognostic immune markers governing treatment success. In this study, 51 sta...