Abstract Human cytomegalovirus (CMV) causes severe disease in immunocompromised individuals. CMV-based vectors are promising candidates vaccination and immunotherapy approaches. Here, we report on our approach to make chimpanzee CMV (CCMV) available for research vector development. We cloned the CCMV genome created a global picture of infection program by multi-omics. Via engineering distinct r...

cytomegalovirus is the most important pathogen affecting transplant recipients and causing significant morbidity and morbidity. the prevalence of cmv  infections in transplant recipient varies from country to country.  the aim of this study was to determine the prognostic value of pcr assay for cmv  detection in patients before keratoplasty.  a total of 23 patient samples enrolled in this study...

recently, using polymerase chain reaction (pcr) technique, the dna of cytomegalovirus was detected from depigmented white patches in patients with vitiligo. the reactivation of infection and occasional anti-cmv igm circulating among patients infected by cytomegalovirus has been reported for years. we have studied 26 patients with clinical signs and symptoms of vitiligo, some of whom had a histo...

cytomegalovirus (cmv) infection is one of the most common infections that affects humans’ cardiovascular system. although the literature includes controversial evidence for any correlation between cmv infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. however, the number of prospective...

background beta-thalassemia patients receive blood products from blood transfusion centers repeatedly. blood transfusion can transmit cytomegalovirus (cmv) and toxoplasma gondii. the aim of this study was serological evaluation of these two infectious agents in thalassemia patients. materials and methods in a cross-sectional study, the enzymelinked immunosorbent assay (elisa) testing was perfor...

recent reports have suggested that cytomegalovirus (cmv) infection may contribute to risk of cardiovascular disease. however, relationship between cmv infection and unstable angina (ua) is controversial and studies about this subject in iran and even region are lacking. the aim of this study was to determine whether unstable angina is related to seropositivity to chronic cytomegalovirus infecti...

This study aimed to determine the seroprevalence of Cytomegalovirus virus (CMV) infection among pregnant women in Ad Dhale'e city, Yemen. A cross-sectional was conducted 130 attended for routine antenatal care Al-Nasser hospital Ad-Dhale'e city. Serum obtained and tested seropositivity CMV IgG IgM using electro-chemiluminescence immunoassays (ECLIA) test. Of blood sample, 122 (93.8 %) 5 (3.8%) ...

Background.  Congenital cytomegalovirus (CMV) infection can cause severe birth defects. The majority of children with congenital CMV are born to CMV-seropositive women; however, transmission from mother to fetus and resulting defects are more likely to occur when mothers experience seroconversion during pregnancy. The objective of this study was to provide a population-based estimate of CMV ser...