cytokine profile

Background and Objectives: Infection with human immunodeficiency virus (HIV) results in dysregulation of the cytokine profile. A switch from a T helper 1 (Th1) to a Th2 cytokine has been proposed as an important factor in progression of HIV infection to AIDS. The aim of the present study was to assess the level of Th1 and Th2 cytokines in HIV infected individuals in order to identify t...

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cytokine gene polymorphisms in iranian patients with beta-thalassemia major

Journal: :iranian journal of immunology 0

morteza bagheri department of molecular biology & genetics, uromia university of medical sciences, uromia, iran ali akbar amirzargar immunogenetic laboratory, department of immunology, school of medicine, tehran university of medical sciences ardeshir ghavamzadeh hematology-oncology and bmt research center, shariati hospital, tehran, iran kamran alimoghadam hematology-oncology and bmt research center, shariati hospital, tehran, iran farideh khosravi immunogenetic laboratory, department of immunology, school of medicine, tehran university of medical sciences bita ansaripour immunogenetic laboratory, department of immunology, school of medicine, tehran university of medical sciences batoul moradi

background: β-thalassemia as a hereditary disease is defined as defective synthesis of β-globin chains, resulting in erythropoiesis abnormalities and severe anemia. different studies have shown that cytokines and cytokine gene polymorphisms play a major role in the pathogenesis of β-thalassemia. single nucleotide polymorphisms (snps) within the promoter region or other regulatory sequences ...

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cytokine profile in the endometrium of normal fertile and women with repeated implantation failure

Journal: :iranian journal of immunology 0

samira rajaei immunology research center, tehran university of medical sciences amir hassan zamani immunology research center, tehran university of medical sciences mahmood jeddi-tehrani monoclonal antibody research center maryam tavakoli immunology research center, tehran university of medical sciences afsaneh mohammadzadeh reproductive biotechnology research center, avicenna research institute, acecr ali dabbagh anesthesiology research center, shahid beheshti university of medical sciences, tehran, iran mahroo mirahmadian

background: repeated implantation failure (rif) is one of the most intricate obstacles in assisted reproduction. the cytokine and chemokine composition of uterine cavity seem to play important roles in the implantation process. objective: to compare the cytokine profile in the endometrium of normal fertile women and those with repeated implantation failure. methods: after enzymatic digestion of...

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