Cytodiagnosis of bony lesions are mainly done where cortical destruction and soft tissue infiltration is evident. Cytodiagnosis of osteolytic lesions with intact cortex is an uncommon procedure, and open bone biopsy is the preferred diagnostic modality. We have done a prospective cytopathological study of such lesions on patients who had come to a Tertiary Teaching Hospital in between February ...

The aim of quality control of a laboratory investigation is to ensure that similar results are obtained on the same material at different centres. To investigate its practicability in cytodiagnosis, the same cytological material was examined independently at six centres. Each centre supplied material from 20 cases, providing a total of 120 cases, ie, 100 cases excluding the donor centre's own m...

The cytodiagnostic acridine orange (AO) fluorescence microscope method was applied to exfoliated material from 4348 cases. The method utilizes increased amounts of cytoplasmic ribonucleic acid (RNA) in malignant cells to demonstrate them in brilliant orange and red fluorescence colors. Scanning smears under low magnification readily revealed the presence of cells with increased fluorescence. Us...

THERE are several varieties of pleural effusion where an examination of the cells in the fluid is as a rule unnecessary. These are the various forms of purulent effusion or empyema. Pus is pus all the world over, and its main scientific interest is not to be found in the cells which it contains, but in the organisms which cause its production and are to be found in it. It makes a great deal of ...

Significant numbers of overdiagnoses of thyroid needle biopsies as "indeterminate" create a risk of surgery for benign disease. Overdiagnoses can be reduced by appropriate criteria and a risk-adapted approach to cytodiagnosis.

This paper presents cytomorphological features of the histoid variety of lepromatous leprosy. Fine needle aspiration of a lepromatous nodule showed cytological features consistent with those of histoid leprosy. Simultaneously, a biopsy of the nodule was also performed and the case confirmed as histoid leprosy. The advantages of the fine needle aspiration technique are that it is simple, quickly...