The synthesis and X-ray single crystal structures of a series of new 4-substituted-1,3selenazol-2-amines is reported. The efficient preparation of these compounds was carried out by two-component cyclization of the selenoureas with equimolar amounts of α-haloketones. The selenoureas were obtained from the reaction of Woollins’ reagent with cyanamides, followed by hydrolysis with water. All new ...

In an earlier communication Siddiqui and Bina [1] reported some extensions of von Braun BrCN reaction on the conessine series of alkaloids, which appeared to provide a novel route for the synthesis of therapeutically active nitrogenous compounds including substituted ureas, diamines, carbinol amines and guanidine derivatives. However, it was noted by them that dimethyl a-napthylamine and diethy...

The synthesis and X-ray single crystal structures of a series of new 4-substituted-1,3-selenazol-2-amines is reported. The efficient preparation of these compounds was carried out by two-component cyclization of the selenoureas with equimolar amounts of α-haloketones. The selenoureas were obtained from the reaction of Woollins' reagent with cyanamides, followed by hydrolysis with water. All new...

An iron-catalyzed [2 + 2 + 2] cycloaddition reaction of diynes and cyanamides at room temperature is reported. Highly substituted 2-aminopyridines were obtained in good to excellent yields with high regioselectivity. Insights toward the reaction process were investigated through in situ IR spectra and control experiments. In this iron-catalyzed cycloaddition reaction, the active iron species wa...