Pulmonary Kaposi's sarcoma is an unusual pre-mortem diagnosis in AIDS patients. During a four-year period, 318 patients with AIDS-associated Kaposi's sarcoma presented to New York University Medical Center; 19 patients were found to have pulmonary involvement. All 19 patients were homosexual men; 18 of these patients presented with cutaneous and/or visceral Kaposi's sarcoma. Seventy-nine percen...

Background Extraskeletal Ewing's sarcoma is a rare malignant tumor of mesenchymal origin, which is histologically similar to primary osseous Ewing's sarcoma. It has been well described in deep soft tissues. However, location in cutaneous or subcutaneous tissue has rarely been reported. Being seen principally in children, it can be seen, rarely, in old men. Case report We present a case of sub...

INTRODUCTION Rarely, the dermatologistmay encounter a primary cutaneous pleomorphic sarcoma (also known as a malignant fibrous histiocytoma), an undifferentiated neoplasm thought to be of mesenchymal origin. These uncommon skin tumors typically manifest as tender subcutaneous nodules. In contrast to primary cutaneous sarcomas, we present a case of a soft tissue pleomorphic sarcomawithmultiple m...

CGS: cutaneous granulocytic sarcoma GS: granulocytic sarcoma IHC: immunohistochemistry KP: Koebner phenomenon MDS: myelodysplastic syndrome MPO: myeloperoxidase PG: pyoderma gangrenosum TGF-b1: transforming growth factor-beta 1 TGF-b1R: transforming growth factor-beta 1 receptor INTRODUCTION Granulocytic sarcoma (GS) is also known as myeloid sarcoma or chloroma because of its green hue caused b...

Langerhans cells are antigen presenting dendritic cells and tumours arising from these are rare. The tumours arising from these dendritic cells are divided into two categories according to a WHO classification: Langerhans cell histiocytosis and Langerhans cell sarcoma. It is the degree of atypia and clinical aggressiveness that distinguishes the two subtypes. Langerhans cell sarcoma (LCS) is a ...

Bronchopulmonary Kaposi's sarcoma (KS) occurs in 20 percent of AIDS patients with cutaneous involvement; however, complete endobronchial occlusion is uncommon. Moreover, bronchopulmonary KS is infrequent in the absence of cutaneous manifestations. We report a case of documented complete endobronchial obstruction by KS without cutaneous involvement.

BACKGROUND Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an immunosuppressive drug used for kidney transplant, exhibits antiangiogenic activity related to impaired production of VEGF (vascular endothelial growth factor), clinical benefit h...

threatening condition which is distributed worldwide. Kaposi sarcoma is the most common malignancy in AIDS patients, and cutaneous Kaposi sarcoma is frequently the initial manifestation of the disease (1). Kaposi sarcoma associated with human immunodeficiency virus (HIV) is usually widely distributed on the skin and may also be widely disseminated internally, frequently with pulmonary involveme...