Abstract Drug eruptions are among the most common diseases of skin. The majority cases benign and self-limited, however particular variants very severe potentially life threatening. A precise rapid diagnosis is essential but can be difficult in some instances as drug may lack specific histological criteria. Furthermore, pitfalls frequent heightened awareness to possible mimicry other skin requi...

OBJECTIVE To evaluate the incidence of adverse cutaneous drug reactions in intensive care unit patients. DESIGN Cohort study. SETTING General adult intensive care unit of an institutional tertiary care hospital. PATIENTS Patients in the intensive care unit during a consecutive 8-month period were examined for adverse cutaneous drug reactions. RESULTS Patients in the intensive care unit ...

BACKGROUND The rate of severe cutaneous adverse drug reactions is low, and these reactions can result in death or disability. An evidence-based epidemiological study of severe cutaneous adverse drug reactions in China has not been reported. OBJECTIVE The aim of this study was to analyze epidemiology and characteristics of severe cutaneous adverse drug reactions of Chinese inpatients during th...

BACKGROUND Cutaneous drug reactions are frequently found. Assessing the clinical and epidemiological profile of severe forms is extremely relevant for their better recognition and management. Few studies have assessed the severe forms of cutaneous drug reactions in patients hospitalized in our setting. OBJECTIVES To assess the clinical and epidemiological aspects of severe cutaneous adverse r...

Cutaneous drug reactions are among the most commonly reported adverse drug reactions. Drugs prescribed by orthopedic surgeons, such as antibiotics, opiates, and nonsteroidal anti-inflammatory drugs, are common offenders. Cutaneous drug reactions can range from those that are common, mild nuisances to those that are rare, severe, and life-threatening. Medications should be considered part of a d...

The present study emphasizes on implementation of the adverse drug reaction reporting and monitoring system, in the Dermatology department of Kasturba Hospital, Manipal, by a clinical pharmacist, using different promotional activities. Documented adverse drug reactions were assessed and analyzed for incidence, purpose of visit, types, drug classes, individual drug causing adverse drug reactions...

Brandon Newell, MD, is Assistant Professor; and Kimberly A. Horii, MD, is Associate Professor, University of Missouri-Kansas City, Children’s Mercy Hospitals and Clinics. Address correspondence to: Brandon D. Newell, MD, of Missouri-Kansas City, Children’s Mercy Hospitals and Clinics, 2401 Gilham Road, Kansas City, MO 64108; fax: 816-983-6710; or e-mail: [email protected]. Dr. Newell and Dr. Hori...

BACKGROUND The aim of this study was to analyze the clinical characteristics of patients with adverse cutaneous drug reactions, which occur when a medicinal product results in cutaneous morbidity. METHODS The study included 308 patients who were diagnosed as having an adverse cutaneous drug reaction during the study period (2007-2009). In 84 cases, histopathologic examination of skin biopsies...