نتایج جستجو برای: cumulative exposure model
تعداد نتایج: 2426432 فیلتر نتایج به سال:
A three compartment physiologically based toxicokinetic model was fitted to human data on benzene disposition. Two separate groups of model parameter derivations were obtained, depending on which data sets were being fitted. The model was then used to simulate five environmental or occupational exposures. Predicted values of the total bone marrow exposure to benzene and cumulative quantity of m...
OBJECTIVES The present study examined the impact of cumulative trauma exposure on current posttraumatic stress disorder (PTSD) symptom severity in a nonclinical sample of adults in their 60s. The predictive utility of cumulative trauma exposure was compared to other known predictors of PTSD, including trauma severity, personality traits, social support, and event centrality. METHOD Community-...
The indiscriminate use of the cumulative exposure metric (the product of intensity and duration of exposure) might bias reported associations between exposure to hazardous agents and cancer risk. To assess the independent effects of duration and intensity of exposure on cancer risk, we explored effect modification of the association of cumulative exposure and cancer risk by intensity of exposur...
in this contribution, linearized dynamic model of cumulative mass fraction (cmf) of potassium nitrate-water seeded continues mixed suspension mixed product removal (cmsmpr) crystallizer is approximated by a simplified model in frequency domain. frequency domain model simplification is performed heuristically using the frequency response of the derived linearized models data. however, the cmf fr...
OBJECTIVES Increased mortality from asthma, chronic bronchitis and emphysema has previously been reported among workers in the silicon carbide (SiC) industry. The objective of the present study was to evaluate the influence of specific exposure factors on mortality from obstructive lung diseases (OLD), using a newly revised job-exposure matrix. MATERIALS AND METHODS 1687 long-term workers emp...
Introduction: Exposure to crystalline silica dust can seriously threaten health of workers engaged in processes such as casting, stone crushing, grinding, construction activities, insulator manufacturing, and glassblowing and sandblasting. The aim of this study was to assess occupational exposure to crystalline silica and to determine the risk of mortality from silicosis and lung cancer in an i...
This paper presents an optimum plan for simple (two stresses) time-step-stress accelerated life tests under the log-logistic model considered appropriate for insulating materials. A log-logistic life distribution with a median that is a log-linear function of stress, and a cumulative exposure model are assumed. The optimum test plan is obtained by minimizing the asymptotic variance of the maxim...
The evaluations of the potential carcinogenicity of metallic chromium and trivalent chromium by several international and national agencies [International Agency for Research on Cancer (IARC), 1990; Agency for Toxic Substances and Disease Registry (ATSDR), 1993; Canadian Environmental Protection Act (CEPA), 1994; United States Environmental Protection Agency (US EPA), 1998; United States Nation...
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