AIM This study evaluated the curative potential of Crinum giganteum in the treatment of schizophrenia using an NMDA-receptor antagonist-induced schizophrenic Wistar rat model. METHODS Twenty-five adult Wistar rats of both sexes of average weights 180 g were divided into two groups: control and schizophrenic rat models. The controls received 0.1 ml of 0. 9% saline, while schizophrenia was indu...

Background Crinum americanum L. popularly known as lily is an ornamental plant that belongs to the family Amaryllidaceae alkaloids presenting with anti-inflammatory, antimicrobial and inhibition acetilcolinisterase. The species Boerhavia paniculata Rich is a plant from the family Nyctaginaceae popularly known as “Pega Pinto” that produces isoflavones that have action antiinflmatórias urinary tr...

A GC-MS analysis of underivatized alkaloids from leaves of Crinum latifolium was performed. From the identified 15 alkaloids, 9 were found for the first time in this plant. Almost all alkaloids belonged to the crinane type. Substantial changes in the methylation and oxidation pattern of the alkaloids at and after flowering were observed.

Eighty-seven methanol extracts of medicinal plants, most of them are currently used in Vietnamese oriental medicine, were screened for NF-κB inhibitory activity. Seven methanol extracts showed strong to moderate inhibitory activity. These include the extracts of Crinum latifolium (leaves), Evodia rutaecarpa (fruits), Polygonum cuspidatum (rhizoma), Perilla ocymoides (leaves), Rubia cordifolia (...

objectives: the aim of present study was to evaluate some effects of crinum zeylanicum (c. zeylanicum) on central nervous system. materials and methods: c. zeylanicum methanolic bulb extract (250-1000 mg/kg orally), 2 mg chlorpromazine and 4 mg diazepam /kg body weight intraperitoneally respectively were tested in mice using irwin test, pentobarbitone-induced sleep test, spontaneous motor activ...