Clindamycin concentrations in gingival crevicular fluid and in blood were determined over a 7-h period and were related to the minimal inhibitory concentrations of this agent for 340 bacterial strains isolated from diseased periodontal sites. The clindamycin levels after administration of single 300-mg oral doses were measured in gingival crevicular fluids by using an agar diffusion bioassay. M...

background: azithromycin (azm) is used in periodontal infections. the present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the hplc method. methods: two groups (n=15) of healthy volunteers participated in this study. the first group received an imported azithromycin (imazm) tablet (250 mg, po) and the second group received an azi...

Background: Azithromycin (AZM) is used in periodontal infections. The present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the HPLC method. Methods: Two groups (n=15) of healthy volunteers participated in this study. The first group received an imported azithromycin (ImAZM) tablet (250 mg, PO) and the second group received an ...

BACKGROUND AND OBJECTIVE The aim of this work was to investigate periodontal status, in relation to inflammatory markers and cortisol, in the gingival crevicular fluid and saliva of a homogenous group of women on long-term sick leave for job-stress related depression in comparison to nondepressed women. MATERIAL AND METHODS The participants comprised 20 women with depression (DSM-IV) (mean ag...

BACKGROUND AND OBJECTIVE A low-grade systemic inflammatory status originating from periodontal infection has been proposed to explain the association between periodontal disease and systemic conditions, including adverse obstetric outcomes. The aim of this study was to evaluate the effect of periodontal therapy during pregnancy on the gingival crevicular fluid and serum levels of six cytokines ...

BACKGROUND Human cytomegalovirus (HCMV) infection is associated with renal transplant failure. Periodontal pockets may be reservoirs for HCMV replication. OBJECTIVES This study was done to determine active HCMV replication in saliva and gingival crevicular fluid of renal transplant patients affected by periodontitis. METHODS HCMV pp67-mRNA amplification was analyzed in oral fluids of 38 tra...

Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...

The purpose of the study Our study was centred on the comparative research of enzymatic and non-enzymatic oxidative status mediators in the crevicular fluid on chronic and aggressive periodontitis patients, compared to periodontal healthy subjects. Materials and methods The study was conducted on 42 patients. They were divided in 3 study groups: chronic periodontitis subjects, aggressive period...

BACKGROUND The aim of this study was to determine the presence of matrix metalloproteinase-8 in the gingival crevicular fluid (GCF) of patients after acute myocardial infarction (AMI). METHODS A total of 48 GCF samples from 20 AMI patients, hospitalized at the Department of Cardiology and Angiology of the Johannes Gutenberg University Mainz, were investigated. Besides the myocardial infarctio...