polyoma virus nephropathy occurs in 3% to 4% of renal transplant recipients, causing graft loss in 50% of cases. the objective of the present study was to explore the effects of age, sex, post-transplantation period and plasma creatinine levels on the polyoma virus infection in kidney transplanted patients. urine samples were collected from 362 patients, centrifuged and microscopic slides prepa...

Co-trimoxazole is a frequently prescribed antibiotic worldwide. It is composed of both trimethoprim and sulfamethoxazol (Sfx) and is used in the treatment and prophylaxis of urinary tract and Pneumocystis jirovecii infections. The Sfx component appears to be nephrotoxic at high doses or doses inappropriately adjusted for glomerular filtration rate (GFR). The trimethoprim component, even at reco...

Background: Measurement of glomerular filtration rate (GFR) and monitoring of it in any patient on nephrotoxic drugs is very important. Recently, cystatin C (cys-C) has been introduced as a better marker for determining and monitoring renal function than creatinine especially in a mild decrease of GFR. This study was done to assess the change of GFR measurement based on serum Cys-C and creatini...

background: due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. however, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. so, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent’s child...

introduction: strength training has an important role in the exercise programs of normal individuals and athletes and it also has numerous benefits on the health of human body and spirit. one of the types of these exercise is eccentric resistance exercise which is associated with negative physiological changes. thus: this study examined the effects of a single bout of eccentric resistance exerc...

diazinon is an organophosphate which is extensively used in trade and agriculture. due to its widespread application, its toxicity is common. several studies have shown that organophosphates are able to induce oxidative stress by generating free radicals and depletion of endogenous antioxidants. pomegranate seed oil (pso) possesses anti-inflammatory and antioxidant effects. in this study, the e...

Background: Immunotherapy is the only specific treatment for scorpion envenomation. In the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (BUN and creatinine) induced by Mesobuthus eupeus (Me) scorpion venom was investigated in anesthetized rabbits. Methods: Twenty four rabbits were randomized into four gro...

background serum creatinine as a classic marker of renal function has several limitations in the detection of renal dysfunction. objectives this study assessed the validity of serum cystatin c as a marker of renal function in critically ill patients with normal serum creatinine. patients and methods eighty adult patients referred to intensive care units with serum creatinine levels < 1.5 mg/dl ...