The effects of hexanoic extracts of Viscum cruciatum Sieber parasitic on Crataegus monogyna Jacq. (I), Crataegus monogyna Jacq. parasitized with Viscum cruciatum Sieber (II), and Crataegus monogyna Jacq. non-parasitized (III), and of a triterpenes enriched fractions isolated from I, II and III (CFI, CFII, CFIII respectively), on the growth of HEp-2 cells have been evaluated. All the samples dem...

objective: cyclosporine (cs), a cyclic undecapeptide with potent immunosuppressive activity, causes several adverse effects including reproductive toxicity. this study aims to examine the ability of crataegus monogyna aqueous fruit extract as an antioxidant to protect against cs-induced reproductive toxicity. materials and methods: in this experimental study, 32 adult male wistar rats were divi...

Cyclophosphamide (CP) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. However, despite its wide spectrum of clinical uses, CP is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. Crataegus monogyna is one of the oldest medicinal plant has been shown to be cytoprotecti...

objective: doxorubicin (dox) is a broad spectrum chemotherapeutic agent used in the treatment of several malignancies. the use of dox in clinical chemotherapy has been restricted due to its diverse toxicities, including reproductive toxicity. crataegus monogyna (c. monogyna) is one of the oldest medicinal plants that have been shown to be cytoprotective because of scavenging free radicals. the ...

cyclophosphamide (cp) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. however, despite its wide spectrum of clinical uses, cp is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. crataegus monogyna is one of the oldest medicinal plant has been shown to be cytoprotecti...

Objective: Doxorubicin (DOX) is a broad spectrum chemotherapeutic agent used in the treatment of several malignancies. The use of DOX in clinical chemotherapy has been restricted due to its diverse toxicities, including reproductive toxicity. Crataegus monogyna (C. monogyna) is one of the oldest medicinal plants that have been shown to be cytoprotective because of scavenging free radicals. The ...

The abundance of scientific evidence has shown that many synthetic drugs can cause serious adverse effects in patients. Recently, the search of natural therapeutic agents with low adverse effects has attracted much attention. In particular, considerable interest has focused on edible and medicinal plants, which play an important role in human diet, and have been used for disease treatment since...

In this investigation, two species of Crataegus (hawthorn) were chosen because their polyphenolic constituents have recently received greater attention for the treatment of patients with severe heart disease. One-year-old plants of hawthorn (Crataegus laevigata and C. monogyna) were subjected to water-deficit (continuous water deprivation), cold (4 degrees C), flooding (immersion of roots of pl...

On the Vidlič mountain, mixed mesophilic mountain beech forests (Fagetum submontanum serbicum) have been recorded at altitudes of 700 - 1000 m, following localities: Crni vrh, Vazganica, Kranjci, Planinarski dom, and Visočka Ržana. Phytocenological research was performed on mentioned localities by Braun-Blanquet method (Braun-Blanquet, 1964). It taken 11 phytocenological plots. Beech (Fagus moe...

Cathepsin cysteine proteases such as cathepsin S are responsible for the unfavorable and irreversible dysregulation of extracellular matrix (ECM) proteolysis found in cardiomyopathy, heart valve diseases atherosclerosis. plays a central role ECM remodeling, which has been implicated development progression cardiovascular diseases. The current study aimed to evaluate aqueous ethanol extracts ber...