Exclusion of acute myocardial infarction preoperatively, particularly in patients undergoing cardiac catheterization, is an important requirement for optimal results following coronary revascularization. Unfortunately, activity of conventionally measured serum enzymes (AST, LDH, total CPK) is frequently raised because of enzyme released from non-cardiac sources during the catheterization proced...

Myocardial creatine phosphokinase (CPK) activity was measured as an indicator of cell viability 24 hours after ligation of the left anterior sescending coronary artery (LAD) in normal myocardium, the entire region supplied by the LAD, and individual samples from the border and center of the infarct. Tissue supplied by the LAD and delineated by dye was carefully dissected from normal tissue alon...

BACKGROUND Poisoning has reported to be a major cause of death and burden of disease in low- and middle-Income countries. Rhabdomyolysis is a common consequence of many poisoning cases and serum creatine phosphokinase (CPK) is a marker for it. The aim of the study was to assess whether the admission creatine phosphokinase in comatose patients with acute poisoning is a predictive factor for the ...

INTRODUCTION Several mechanisms were introduced as causes of serum creatinine phosphokinase (CPK) raise in intoxicated patients. This study aimed to assess the relationship between serum CPK level in the first 24 hours and baseline characteristics as well as outcomes of these patients. METHODS This one year retrospective cross-sectional study was conducted on all intoxicated patients, who wer...

at postmortem 1 wk later. In control dogs, the gross infarct size at postmortem averaged 63.8±7.3% of that predicted from the acutely injured zone. However, in reperfused hearts the average gross infarct size at 1 wk was only 10.2+4.4% of that predicted. Transmural specimens were obtained at autopsy for histology and measurement of myocardial creatine phosphokinase (CPK) activity from sites ini...

To determine the prognostic value of Creatine Phosphokinase (CPK) levels after acute myocardial infarction in patients thought to be at low risk of death or major complications, 94 consecutive patients with definite myocardial infarction were divided into two groups according to peak CPK levels. Group I contained 23 patients with a peak CPK of less than 1000 units and Group II contained 71 pati...

In this paper, we introduce a new estimation method for total creatine phosphokinase release based on a physiological model of the serum creatine phosphokinase (CPK) activity change that can be used to estimate the total CPK release accurately, as early as possible, without frequent blood sampling. The physiological model and a new calculation method were applied to the serum CPK activity chang...

Determination of serum creatine phos~hokinase (CPK; EC 2.7.3.2.) is important ill laboratory diagnosis of myocardial infarction (M') and skeletal muscle disorders (7). Two recent reports suggest that administration of corticosteroids decreases serum CPK activity (1.5). If patients with MI and myopathies are given. corticosteroids as some of them are the corticostEroids may ~revent the expected ...

Polycystic kidney disease is a disorder marked by aberrant renal tubular epithelial cell proliferation and transport abnormalities. Sphingolipids are ubiquitous membrane components implicated in several cellular functions including cell membrane sorting, signaling, growth, ion transport, and adhesion. To investigate a potential pathogenic role for sphingolipids in cystic kidney disease, we stud...