purpose: to compare the effects of short-tem and long-term systemic corticosteroids in the treatment of confirmed ocular toxoplasmosis. methods: this randomized comparative clinical trial was performed on 69 patients with confirmed active ocular toxoplasmosis with typical clinical manifestations. the subjects were randomly assigned to receive either 10 days (group a, 33 cases) or 4-6 weeks (gro...

pemphigus vulgaris (pv) is often complicated by osteoporosis. although corticosteroid therapy undoubtedly plays a causative role, inflammation associated with pv may also contribute to osteoporosis. this study was designed to determine the prevalence of osteoporosis in patients with pv before corticosteroid therapy and to compare these findings with those reported previously in healthy voluntee...

a b s t r a c t a few case reports of coinfections with nocardia and mycobacterium tuberculosis (tb) have previously been published in the literature. we report on a case of concomitant pulmonary nocardiosis and tuberculosis, in a recently diagnosed 55-year-old woman, with rheumatoid arthritis, who had been taking a short course of a low dose corticosteroid. the patient was treated with a combi...

background: osteonecrosis (on) is known to be one of the most disabling complications following corticosteroid (cs) medications. however, evidence regarding risk of asymptomatic prevalence of on among different diseases and the impact of variable steroid regimens are conflicting. we aimed to determine the prevalence of on of femoral head in asymptomatic patients with systemic rheumatic diseases...

To analyze the clinical characteristics of corticosteroid-resistant refractory Mycoplasma pneumoniae pneumonia (RMPP) and explore the related factors that predict corticosteroid-resistant RMPP. Retrospective analysis of 183 children with RMPP in our hospital admitted between January 1, 2012, and December 31, 2014 was performed. Of the 183 RMPP cases, 36 (19.7%) were corticosteroid-resistant RMP...

purpose : the aim of this study is to measure the endogenous cortisol levels in the patients with central serous chorioretinopathy (cscr) and also, evaluate the short-term effect of oral ketoconazole in the treatment of both acute and chronic cscr. methods : in this prospective interventional case series 12 patients with acute cscr and 7 patients with chronic cscr (including one patient with bi...

Family physicians considering corticosteroid injections as part of a comprehensive treatment plan for musculoskeletal diagnoses will find few high-quality studies to assist with evidence-based decision making. Most studies of corticosteroid injections for the treatment of osteoarthritis, tendinopathy, bursitis, or neuropathy include only small numbers of patients and have inconsistent long-term...

A 24 year old woman with bilateral oral white patches was referred to dermatology clinic. Her chief complaint was mouth burning. Pathological report of cut section biopsy from oral mucosa was in favor of lichen planus. Intralesional corticosteroid injection and it's subsequent systemic administration 30 mg/ daily for one month showed no improvement. Therefore a combination of systemic corticost...